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905747

Sigma-Aldrich

Gold nanospheres

100 nm, FITC and NHS functionalized, powder

Synonym(s):

Dye labeled gold nanoparticles, FITC labeled gold nanospheres, FITC tagged gold nanospheres, Fluorescein isothiocyanate labeled gold nanospheres, Fluorescent labeled gold nanoparticles

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

nanospheres
powder

storage temp.

2-8°C

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General description

Gold nanospheres (AuNS) (100nm, FITC and NHS functionalized powder) are gold nanoparticles with unique properties which include biocompatibility, easy surface modification, and excellent photothermal conversion. They can be synthesized by a variety of methods such as galvanic replacement of gold nanoparticles, templated galvanic replacement of silver for gold, and electrochemical methods.

Application

Owing to size and shape dependent quantum effects, the gold nanoparticles exhibit unique surface plasmon resonance absorption, scattering, fluorescence, and photothermal properties which render them suitable for applications in catalysis, chemical sensing, biosensing , cellular and bioimaging, drug and gene delivery, and photothermal therapy. The fluorescent labeling of gold nanoparticles have been shown to cause emission enhancement in fluorophores. This makes the fluorescence tagged gold nanoparticles a dual mode nanoprobe for drug delivery and bioimaging applications.

Legal Information

Product of Nanopartz Inc.

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GHS07

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Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Preparation, modification, and application of hollow gold nanospheres
Ren Q, et al.
Journal of Nanomaterials, 2015 (2015)
Fluorescently Labeled Gold Nanoparticles with Minimal Fluorescence Quenching.
Lu Y, et al.
The Journal of Physical Chemistry C, 114, 17446-17446 (2010)
Byoungjin Kim et al.
Nature nanotechnology, 5(6), 465-472 (2010-04-13)
Nanoparticles have great potential as controllable drug delivery vehicles because of their size and modular functionality. Timing and location are important parameters when optimizing nanoparticles for delivery of chemotherapeutics. Here, we show that gold nanoparticles carrying either fluorescein or doxorubicin
Nuri Oh et al.
ACS nano, 8(6), 6232-6241 (2014-05-20)
Significant quantities of synthetic nanoparticles circulating in the body are cleared and retained for long periods of time in the resident macrophages of the mononuclear phagocytic system (MPS), increasing the likelihood of nanoparticle-mediated chronic toxicity. To date, there has been
Gold nanoparticles in chemical and biological sensing.
Krishnendu Saha et al.
Chemical reviews, 112(5), 2739-2779 (2012-02-03)
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