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905747

Sigma-Aldrich

Gold nanospheres

100 nm, FITC and NHS functionalized, powder

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Synonym(s):
Dye labeled gold nanoparticles, FITC labeled gold nanospheres, FITC tagged gold nanospheres, Fluorescein isothiocyanate labeled gold nanospheres, Fluorescent labeled gold nanoparticles

form

nanospheres
powder

storage temp.

2-8°C

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Gold nanospheres

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Gold nanospheres

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

Gold nanospheres (AuNS) (100nm, FITC and NHS functionalized powder) are gold nanoparticles with unique properties which include biocompatibility, easy surface modification, and excellent photothermal conversion. They can be synthesized by a variety of methods such as galvanic replacement of gold nanoparticles, templated galvanic replacement of silver for gold, and electrochemical methods.

Application

Owing to size and shape dependent quantum effects, the gold nanoparticles exhibit unique surface plasmon resonance absorption, scattering, fluorescence, and photothermal properties which render them suitable for applications in catalysis, chemical sensing, biosensing , cellular and bioimaging, drug and gene delivery, and photothermal therapy. The fluorescent labeling of gold nanoparticles have been shown to cause emission enhancement in fluorophores. This makes the fluorescence tagged gold nanoparticles a dual mode nanoprobe for drug delivery and bioimaging applications.

Legal Information

Product of Nanopartz Inc.

Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Preparation, modification, and application of hollow gold nanospheres
Ren Q, et al.
Journal of Nanomaterials, 2015 (2015)
Fluorescently Labeled Gold Nanoparticles with Minimal Fluorescence Quenching.
Lu Y, et al.
The Journal of Physical Chemistry C, 114, 17446-17446 (2010)
Byoungjin Kim et al.
Nature nanotechnology, 5(6), 465-472 (2010-04-13)
Nanoparticles have great potential as controllable drug delivery vehicles because of their size and modular functionality. Timing and location are important parameters when optimizing nanoparticles for delivery of chemotherapeutics. Here, we show that gold nanoparticles carrying either fluorescein or doxorubicin
Xiaohua Huang et al.
Journal of the American Chemical Society, 128(6), 2115-2120 (2006-02-09)
Due to strong electric fields at the surface, the absorption and scattering of electromagnetic radiation by noble metal nanoparticles are strongly enhanced. These unique properties provide the potential of designing novel optically active reagents for simultaneous molecular imaging and photothermal
Parwathy Chandran et al.
Nanotoxicology, 11(4), 507-519 (2017-04-20)
This study investigated the role of nanoparticle size and surface chemistry on biocorona composition and its effect on uptake, toxicity and cellular responses in human umbilical vein endothelial cells (HUVEC), employing 40 and 80 nm gold nanoparticles (AuNP) with branched polyethyleneimine

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