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Sigma-Aldrich

Poly(ethylene oxide)-block-poly(butylene oxide)

PEG average Mn 2,000, average Mn 5,000 (PBO)

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Synonym(s):
PBO-PEO, PEG-PBO, PEO-PBO
Linear Formula:
CH3O(C2H4O)m(C4H8O)nH

form

solid

Quality Level

mol wt

PEG average Mn 2,000 (by NMR)
PEG average Mn 2,000
average Mn 5,000 (PBO(by NMR))
average Mn 5,000 (PBO)

color

white to off-white

PDI

≤1.3 (by GPC)

storage temp.

2-8°C

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This Item
372781372773181986
Poly(ethylene oxide) average Mv ~1,000,000 (nominal), powder

372781

Poly(ethylene oxide)

Poly(ethylene oxide) average Mv 400,000 (nominal), powder

372773

Poly(ethylene oxide)

Poly(ethylene oxide) average Mv 100,000 (nominal), powder

181986

Poly(ethylene oxide)

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

mol wt

PEG average Mn 2,000 (by NMR)

mol wt

average Mv ~1,000,000 (nominal)

mol wt

average Mv 400,000 (nominal)

mol wt

average Mv 100,000 (nominal)

color

white to off-white

color

-

color

-

color

-

PDI

≤1.3 (by GPC)

PDI

-

PDI

-

PDI

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

Application

Poly(ethylene oxide)-block-poly(butylene oxide) is an amphiphilic block copolymer that shows good biocompatibility. This type of polymers can self-assemble into micelles of various shapes at low concentration. It has been used as nanocarriers to solubilize and delivery hydrophobic drugs.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Guilin Cheng et al.
Colloids and surfaces. B, Biointerfaces, 181, 822-829 (2019-06-28)
Biodegradable polymeric nanoparticles (NPs) have been used frequently as nanocarriers for anticancer drugs. Linoleic acid conjugated SN38 (LA-SN38)-loaded NPs (EBNPs) were developed using biodegradable poly (ethylene oxide)-poly (butylene oxide) (PEO-PBO) diblock copolymer by titration hydration method without using a toxic
Lijiang Wang et al.
Colloids and surfaces. B, Biointerfaces, 161, 464-470 (2017-11-13)
An amphiphilic block copolymer poly(ethylene oxide)-b-poly(butylene oxide) (PEO-PBO) was evaluated as a carrier for therapeutic delivery of paclitaxel (PTX). PEO-PBO and PTX form nanoparticles (NPs) by self-assembly upon hydration. The size of these NPs was about 92.71nm and the zeta
Mahmoud Elsabahy et al.
Biomacromolecules, 8(7), 2250-2257 (2007-06-21)
Poly(ethylene oxide)-block-poly(styrene oxide) (PEO-b-PSO) and PEO-b-poly(butylene oxide) (PEO-b-PBO) of different chain lengths were synthesized and characterized for their self-assembling properties in water by dynamic/static light scattering, spectrofluorimetry, and transmission electron microscopy. The resulting polymeric micelles were evaluated for their ability

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