MilliporeSigma
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918741

Sigma-Aldrich

TissueFab® bioink 

(Gel)ma -VIS/405nm, low endotoxin

Synonym(s):
Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl

Quality Level

description

suitable for 3D bioprinting applications
with LAP photoinitiator

sterility

sterile-filtered

form

viscous liquid

impurities

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)
<50 EU/mL Endotoxin

color

colorless to pale yellow

particle size

0.2 μm

pH

6.5-7.5

application(s)

3D bioprinting

storage temp.

2-8°C

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description

suitable for 3D bioprinting applications

description

suitable for 3D bioprinting applications

description

-

description

HNMR in D2O at 40°C

sterility

sterile-filtered

sterility

-

sterility

-

sterility

-

form

viscous liquid

form

gel form (Viscous)

form

-

form

(viscous liquid to gel)

impurities

≤5 CFU/g Bioburden (Fungal)

impurities

≤5 CFU/g Bioburden (Fungal), ≤5 CFU/g Bioburden (Total Aerobic)

impurities

-

impurities

<5 CFU/g Bioburden (Fungal), <5 CFU/g Bioburden (Total Aerobic), <50 EU/mL Endotoxin

color

colorless to pale yellow

color

colorless to pale yellow

color

-

color

pale yellow to colorless

particle size

0.2 μm

particle size

-

particle size

-

particle size

-

Application

TissueFab® GelMA-Vis-LAP bioink is a gelatin methacryloyl (GelMA) based bioink for 3D bioprinting applications. LAP is used as the photoinitiator, which allows blue light photocrosslinking of the printed structure. The formulation is optimized for high printing fidelity and cell viability. The low endotoxin level of this product is lower than 50 EU/mL.

Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Legal Information

TISSUEFAB is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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