923494

iPrMPhos

• Synonym(s): 1-Diadamantylphosphino-1′-diisopropylphosphinoferrocene
• Empirical Formula (Hill Notation): C₃₆H₅₂FeP₂
• Molecular Weight: 602.59
• UNSPSC Code: 12352128
• NACRES: NA.21

Properties

• form: powder or chunks
• Quality Level: 100
• reaction suitability: reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• mp: 172-175 °C
• functional group: phosphine

Description

Application

iPrMPhos is an unsymmetrical ferrocene-based phosphine ligand. The MPhos series of ligands are unsymmetrical diphosphino-ferrocenes bearing a bulky adamantyl group. Pd catalysts containing iPrMPhos can be used for a variety of cross-coupling transformations, including Suzuki coupling, C-P coupling, and Csp²-Csp³ coupling. Demonstrated Csp²-Csp³ couplings include Murahashi-Feringa Coupling (Alkyl-Li), Kumada-Corriu coupling (Alkyl-MgX), Negishi coupling (Alkyl-ZnX) and Suzuki–Miyaura coupling (Alkyl-B(OR₂)).

Learn more about MPhos ligands and catalysts

Other Notes

Tunable Unsymmetrical Ferrocene Ligands Bearing a Bulky Di-1-adamantylphosphino Motif for Many Kinds of Csp²–Csp³ Couplings

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable