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B1253

Sigma-Aldrich

Butylated hydroxyanisole

≥98.5%

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Synonym(s):
2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA
Linear Formula:
(CH3)3CC6H3(OCH3)OH
CAS Number:
Molecular Weight:
180.24
EC Number:
MDL number:
NACRES:
NA.22

vapor density

6.2 (vs air)

assay

≥98.5%

form

powder

autoignition temp.

599 °F

mp

58-60 °C (lit.)

InChI

1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3

InChI key

MRBKEAMVRSLQPH-UHFFFAOYSA-N

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1 of 4

This Item
W21830849886PHR1304
vibrant-m

B1253

Butylated hydroxyanisole

vibrant-m

W218308

Butylated hydroxyanisole

vibrant-m

49886

Butylated hydroxyanisole

vibrant-m

PHR1304

Butylated hydroxyanisole

assay

≥98.5%

assay

99%

assay

-

assay

-

mp

58-60 °C (lit.)

mp

58-60 °C (lit.)

mp

58-60 °C (lit.)

mp

58-60 °C (lit.)

form

powder

form

-

form

-

form

-

vapor density

6.2 (vs air)

vapor density

6.2 (vs air)

vapor density

6.2 (vs air)

vapor density

6.2 (vs air)

autoignition temp.

599 °F

autoignition temp.

599 °F

autoignition temp.

599 °F

autoignition temp.

599 °F

General description

Butylated hydroxyanisole is mainly used as a synthetic antioxidant in food and cosmetics. It is being extensively studied for potential toxicity.

Other Notes

Mixed isomers (minimum 90% 3-isomer/9% 2-isomer)

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

241.9 °F - Pensky-Martens closed cup

flash_point_c

116.6 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes
Thompson, David and Moldeus, Peter
Biochemical Pharmacology, 37(11), 2201-2207 (1988)
Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene.
A L Branen
Journal of the American Oil Chemists' Society, 52(2), 59-63 (1975-02-01)
Stefanie D Roth et al.
PloS one, 7(9), e44505-e44505 (2012-09-14)
Inefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production. Here we investigated the trafficking of factor VIII (FVIII), which is affected in the coagulation disorder hemophilia A. We
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Yann Malato et al.
Gastroenterology, 143(6), 1597-1608 (2012-08-28)
The transcription factor nuclear factor κB (NF-κB) is activated by the IκB kinase complex. The regulatory subunit of this complex, NF-κB essential modifier (NEMO or IKBKG), is a tumor suppressor. Hepatocyte-specific deletion of NEMO induces chronic liver inflammation that leads

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