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JKA5078

Sigma-Aldrich

HO-PEG5K-NHS

average Mn 5,000

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Synonym(s):
HO-PEG-NHS, Hydroxyl-PEG-NHS Ester, Polyethylene glycol
Linear Formula:
HO(CH2CH2O)nCH2COOC4H2O2N
NACRES:
NA.23

form

solid

mol wt

average Mn 5,000

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

polymer architecture

shape: linear
functionality: heterobifunctional

storage temp.

−20°C

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HO-PEG5K-NHS average Mn 5,000

JKA5078

HO-PEG5K-NHS

HO-PEG1K-NH2 HCl Salt, average Mn 1,000

JKA5234

HO-PEG1K-NH2

HO-PEG20K-NH2 HCl Salt, average Mn 20,000

JKA5158

HO-PEG20K-NH2

HS-PEG5K-NH2 HCl Salt, average Mn 5,000

JKA5145

HS-PEG5K-NH2

form

solid

form

solid

form

solid

form

solid

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive, reagent type: cross-linking reagent
reactivity: thiol reactive

mol wt

average Mn 5,000

mol wt

average Mn 1,000

mol wt

average Mn 20,000

mol wt

average Mn 5,000

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

General description

Hydroxyl-PEG-NHS Ester (HO-PEG-NHS) is hydrophilic in nature.

Application

HO-PEG-NHS may be conjugated on to a hydrophobic H40-PLA-COOH molecule to form H40-PLA-PEG-Apt) (aptamer-conjugated). Other applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization.
Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer.
Xu W, et al.
Biomaterials, 34(21), 5244-5253 (2013)
Ahmet Kertmen et al.
Langmuir : the ACS journal of surfaces and colloids, 35(15), 5281-5293 (2019-03-27)
Numerous glutamine analogues have been reported as irreversible inhibitors of the glucosamine-6-phosphate (GlcN-6-P) synthase in pathogenic Candida albicans in the last 3.5 decades. Among the reported inhibitors, the most effective N3-(4-methoxyfumaroyl)-l-2,3-diaminopropanoic acid (FMDP) has been extensively studied in order to

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