L050030

Cap B

configured for ABI

• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• type: for DNA synthesis
• Quality Level: 200
• product line: Proligo Reagents
• form: liquid
• storage condition: dry at room temperature
• impurities: ≤200 ppm water content (Karl Fischer)
• color: clear
• suitability: conforms to structure (GC, Formulation)
• compatibility: configured for ABI

Description

General description

Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Preparation Note

Tetrahydrofurane / N-Methylimidazole 84/16 (v/v)

Other Notes

Cap B solution, containing tetrahydrofuran (THF) and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Lutidine is applied as a mild base while NMI provides a powerful acylation catalyst.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H314,H335,H336,H351,H361d
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 6.1 °F
• flash_point_c: -14.4 °C