L060080

Oxidizer

0.02 M, configured for PerkinElmer, configured for Polygen

• Synonym(s): Oxidizer
• MDL number: MFCD00677190
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• type: for DNA synthesis
• product line: Proligo Reagents
• form: liquid
• storage condition: dry at room temperature
• concentration: 3.9-4.7 g/L (Iodine content, titration)
• technique(s): DNA synthesis: suitable
• color: clear, brownish solution
• bp: 65—115 °C/1,013 hPa
• compatibility: configured for PerkinElmer; configured for Polygen

Description

General description

Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine, and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor. The product configured for PerkinElmer and Polygen belongs to Expedite^™ Formulation.

Preparation Note

Tetrahyrofurane/Water/Pyridine/Iodine 90.54/9.05/0.41/0.43 (v/v/v/w)

Legal Information

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H335,H336,H351
• pcodes: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: -2.0 °F - closed cup
• flash_point_c: -18.9 °C - closed cup