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P74370

Sigma-Aldrich

2-Pyrrolidinone

99%

Synonym(s):
2-Pyrrolidone, Butyrolactam
Empirical Formula (Hill Notation):
C4H7NO
CAS Number:
Molecular Weight:
85.10
Beilstein:
105241
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

2.9 (vs air)

Quality Level

Assay

99%

form

solid

refractive index

n20/D 1.487 (lit.)

bp

245 °C (lit.)

mp

23-25 °C (lit.)

solubility

H2O: miscible (completely)

density

1.12 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCN1

InChI

1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)

InChI key

HNJBEVLQSNELDL-UHFFFAOYSA-N

Gene Information

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This Item
833008.07041Y0000659
2-Pyrrolidinone 99%

Sigma-Aldrich

P74370

2-Pyrrolidinone

2-Pyrrolidinone purum, ≥98.0% (GC)

Sigma-Aldrich

83300

2-Pyrrolidinone

2-Pyrrolidone for synthesis

Sigma-Aldrich

8.07041

2-Pyrrolidone

Pyrrolidone European Pharmacopoeia (EP) Reference Standard

Y0000659

Pyrrolidone

form

solid

form

solid

form

solid

form

-

refractive index

n20/D 1.487 (lit.)

refractive index

n20/D 1.487 (lit.)

refractive index

-

refractive index

n20/D 1.487 (lit.)

bp

245 °C (lit.)

bp

245 °C (lit.)

bp

-

bp

245 °C (lit.)

mp

23-25 °C (lit.)

mp

23-25 °C (lit.)

mp

25.5 °C (External MSDS)

mp

23-25 °C (lit.)

solubility

H2O: miscible (completely)

solubility

H2O: miscible (completely)

solubility

-

solubility

-

Application

2-Pyrrolidinone is a γ-lactam that can undergo copolymerization with other lactams to form polyamides.

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

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Anionic copolymerization of lactams.
Kricheldorf H R, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 16(9), 2253-2264 (1978)
13C?NMR sequence analysis. 19. Anionic copolymerization of ??butyrolactam, ??valerolactam, and caprolactam at low temperatures.
Kricheldorf H R, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 20(9), 2353-2370 (1982)
M Göbbels et al.
Ophthalmology, 99(6), 873-878 (1992-06-01)
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Xueying Sun et al.
Cancer gene therapy, 12(1), 35-45 (2004-10-16)
The success of surgery to remove primary tumors can be compromised by the subsequent outgrowth of metastases. It is recognized that primary tumors secrete antiangiogenic factors that suppress the outgrowth of their daughter metastases. In accord we show here that
Ryo Shintani et al.
Chemical communications (Cambridge, England), 48(79), 9936-9938 (2012-09-01)
A palladium-catalyzed asymmetric synthesis of 2-pyrrolidinones with a quaternary stereocenter at the 3-position has been achieved by the reaction of γ-methylidene-δ-valerolactones with alkyl isocyanates. High enantioselectivity has been realized by employing a newly synthesized chiral phosphoramidite ligand.

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