Skip to Content
MilliporeSigma
All Photos(1)

Documents

C7017

Sigma-Aldrich

Choline chloride

≥99%

Synonym(s):

(2-Hydroxyethyl)trimethylammonium chloride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
Beilstein/REAXYS Number:
3563126
EC Number:
MDL number:
UNSPSC Code:
50501514
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Quality Level

assay

≥99%

form

powder

color

white

mp

302-305 °C (dec.) (lit.)

lipid type

phospholipids

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.

Application

Choline chloride has been used:
  • in choline release assay
  • as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
  • as a standard to analyse interrelationships between methionine and choline metabolism

Biochem/physiol Actions

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Substrates

Choline acetyltransferase substrate

also commonly purchased with this product

Product No.
Description
Pricing

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Pathophysiological roles and clinical importance of biomarkers in acute coronary syndrome
Chan CP and Rainer TH
Advances in Clinical Chemistry, 59, 23-63 (2013)
Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain
Thirunavukkarasu K, et al.
Osteoarthritis and Cartilage, 25(6), 935-942 (2017)
Clinical biochemistry of domestic animals (2008)
Encyclopedia of Food Sciences and Nutrition (Second Edition) (2003)
Rumen-protected choline for dairy cows: the in situ evaluation of a commercial source and literature evaluation of effects on performance and interactions between methionine and choline metabolism
Brusemeister F and Sudekum KH
Animal Research, 55(2), 93-104 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service