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01480

Sigma-Aldrich

Acetylthiocholine iodide

≥99.0% (AT)

Synonym(s):

(2-Mercaptoethyl)trimethylammonium iodide acetate

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About This Item

Linear Formula:
CH3COSCH2CH2N(CH3)3I
CAS Number:
1866-15-5
Molecular Weight:
289.18
Beilstein/REAXYS Number:
3916578
EC Number:
217-474-1
MDL number:
MFCD00011819
UNSPSC Code:
12352204
PubChem Substance ID:
329747298
NACRES:
NA.83

Quality Level

100

assay

≥99.0% (AT)

ign. residue

≤0.05%

mp

205-210 °C (lit.)
205-210 °C

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NTBLZMAMTZXLBP-UHFFFAOYSA-M

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Application

Acetylthiocholine iodide has been used as a substrate to determine anticholinesterase activity.
Substrate for the colorimetric determination of acetylcholinesterase activity.

Substrates

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 80, 114-129 (2015-03-15)
Herein we report on the comprehensive chemical analysis of the essential oils obtained from above- and underground parts of a previously unreported chemotype of Achillea falcata L. (Asteraceae) and, for the first time, on the biological/toxicological profile of its dominant/newly
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Exposure to the nerve agent soman is difficult to treat due to the rapid dealkylation of the soman-acetylcholinesterase (AChE) conjugate known as aging. Oxime antidotes commonly used to reactivate organophosphate inhibited AChE are ineffective against soman, while the efficacy of
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Fitoterapia, 98, 117-123 (2014-07-30)
Three new 2-(2-phenylethyl)chromone derivatives (1-3), together with thirteen known ones (4-16), were isolated from the EtOAc extract of Chinese agarwood induced by artificial holing, originating from Aquilaria sinensis (Lour.) Gilg (Thymelaeaceae). The chemical structures of the new compounds were identified
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Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(11), 1303-1309 (2014-08-31)
Garcinia mangostana is a well-known tropical plant found mostly in South East Asia. The present study investigated acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of G. mangostana extract and its chemical constituents using Ellman's colorimetric method. Cholinesterase inhibitory-guided approach led
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