Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

A5751

Sigma-Aldrich

Acetylthiocholine iodide

≥98% (TLC), powder or crystals

Synonym(s):

(2-Mercaptoethyl)trimethylammonium iodide acetate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3COSCH2CH2N(CH3)3I
CAS Number:
1866-15-5
Molecular Weight:
289.18
Beilstein/REAXYS Number:
3916578
EC Number:
217-474-1
MDL number:
MFCD00011819
UNSPSC Code:
12352204
PubChem Substance ID:
24891015
NACRES:
NA.83

Quality Level

100

assay

≥98% (TLC)

form

powder or crystals

color

white

mp

205-210 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

SMILES string

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NTBLZMAMTZXLBP-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Application

Acetylthiocholine iodide has been used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. It has also been used as a component in phosphate buffer (PB) for cholinesterase assay.
Substrate for the colorimetric determination of acetylcholinesterase activity.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

An integrated addition and interaction model for assessing toxicity of chemical mixtures
Rider CV and LeBlanc GA
Toxicological Sciences, 87(2), 520-528 (2005)
The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space
Perez GR, et al.
The Journal of Biological Chemistry, 287(51), 43108-43115 (2012)
Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease
Lin HQ, et al.
Chemico-Biological Interactions, 175(1-3), 352-354 (2008)
Effect of short-term exposure to chlorpyrifos on developmental parameters and biochemical biomarkers in Chironomus riparius Meigen
Callaghan A, et al.
Ecotoxicology and Environmental Safety, 50(1), 19-24 (2001)
Venkaiah Betapudi et al.
Science translational medicine, 12(527) (2020-01-24)
Chemical warfare nerve agents are organophosphorus chemical compounds that induce cholinergic crisis, leaving little or no time for medical intervention to prevent death. The current chemical treatment regimen may prevent death but does not prevent postexposure complications such as brain
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service