QBD10219

Biotin-dPEG^®₄-hydrazide

• Synonym(s): 21-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-4,7,10,13-tetraoxa-16-azaheneicosanoic acid hydrazide, Polyethylene glycol
• Empirical Formula (Hill Notation): C₂₁H₃₉N₅O₇S
• CAS Number: 756525-97-0
• Molecular Weight: 505.63
• UNSPSC Code: 12352125
• PubChem Substance ID: 329823896
• NACRES: NA.22

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: carbonyl reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCNC(CCCCC1SCC(C1N2)NC2=O)=O)NN

Description

Features and Benefits

Biotin-dPEG^®₄-hydrazide allows biotin labeling of molecules with free aldehydes or ketones. Biotin-dPEG^®₄-hydrazide reacts to form a hydrazones. This reagent is highly useful for labeling carbohydrates, glycoproteins, and other molecules with biotin following oxidation of the carbohydrate or glycan with sodium periodate or by chemical installation of an aldehyde or ketone on the target molecule. The dPEG^® spacer is a single molecular weight PEG that provides excellent water solubility while extending the biotin moiety away from the surface of the labeled molecule for enhanced binding to avidin or streptavidin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable