QBD10401

NHS-dPEG^®₄-( m-dPEG^®₁₂)₃-ester

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₁₀₈H₂₀₆N₆O₅₂
• CAS Number: 1334178-03-8
• Molecular Weight: 2420.80
• MDL number: MFCD16621418
• UNSPSC Code: 12352108
• PubChem Substance ID: 329823925
• NACRES: NA.22

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• polymer architecture: shape: branched; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C

Description

Features and Benefits

NHS-dPEG^®₄-(m-dPEG₁₂)₃-ester is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. These dPEG^® products consist of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG^® branches. All of these dPEG^® products are hydrophilic, non-immunogenic, single molecular weight compounds. N-hydroxysuccinimide (NHS) group reacts with free amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable