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QBD10492

Sigma-Aldrich

Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3

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Empirical Formula (Hill Notation):
C136H270N6O66
Molecular Weight:
3045.60
PubChem Substance ID:
NACRES:
NA.22

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carbonyl reactive

polymer architecture

shape: branched
functionality: homofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCOCCON)=O

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1 of 4

This Item
QBD10288QBD10318QBD11305
m-dPEG®12-amine

QBD10288

m-dPEG®12-amine

m-dPEG®24-amine

QBD10318

m-dPEG®24-amine

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

polymer architecture

shape: branched
functionality: homofunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: heterobifunctional

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carbonyl reactive

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carboxyl reactive

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

Features and Benefits

Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3 is a branched dPEG® reagent that is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG® branches. The numbers following dPEG® are the exact number of repeat units in the linear chain. This dPEG® product is hydrophilic, non-immunogenic, single molecular weight compound. The aminooxy functional group reacts with aldehydes and ketones to form oxime bonds.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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