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Key Documents

S4007

Sigma-Aldrich

Sodium iodate

≥99%

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About This Item

Linear Formula:
NaIO3
CAS Number:
Molecular Weight:
197.89
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.22

assay

≥99%

density

4.28 g/mL at 25 °C (lit.)

SMILES string

[Na+].[O-]I(=O)=O

InChI

1S/HIO3.Na/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1

Inchi Key

WTCBONOLBHEDIL-UHFFFAOYSA-M

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Application

Sodium iodate (NaIO3) can be used as an oxidant in the following processes:     
  • NaIO3/neutral Al2O3 catalytic system is used to synthesize a variety of aromatic, aliphatic, and alicyclic disulfides via oxidation of the corresponding thiols.      
  • NaIO3/Na2SO3/HCl is used in the preparation of 2-amino-1-iodonaphthalene by iodination of 2-naphthylamine.
  • NaIO3/acetic anhydride or glacial acetic acid is used in aromatic oxidative iodination reactions.

pictograms

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Ox. Sol. 2 - Skin Sens. 1

Storage Class

5.1B - Oxidizing hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simple Oxidation of Thiols with Sodium Iodate under Solid-Solution Biphasic Conditions
Hirano M, et al.
Journal of chemical research. Synopses, (12), 816-817 (1998)
Iodination of both deactivated and activated arenes with sodium periodate or sodium iodate as the oxidants
Lulinski P and Skulski L
Bulletin of the Chemical Society of Japan, 73(4), 951-956 (2000)
Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene
Taldone T, et al.
Synthetic Communications, 42(5), 635-638 (2012)
Jie Huang et al.
Molecular vision, 26, 494-504 (2020-07-09)
To observe the effects of tetramethylpyrazine (TMP) on mice retinas injured by sodium iodate (NaIO3). Male mice (n = 45) were randomly divided into three groups: the control group (Group C), the NaIO3-degenerated group (Group I), and the TMP-treated group
Luisa M Franco et al.
Investigative ophthalmology & visual science, 50(8), 4004-4010 (2009-04-03)
To correlate damage to the retinal pigment epithelium (RPE) with decreased visual function after the systemic administration of sodium iodate (NaIO(3)). Damage was produced in mice by injection of 15, 25, or 35 mg/kg NaIO(3). Visual function was assessed with

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