H-105
17α-Hydroxypregnenolone solution
100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
(Snap-N-Spike®)
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in methanol
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
clinical testing
format
single component solution
storage temp.
−20°C
InChI
1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3/t15-,16+,17-,18-,19-,20-,21-/m0/s1
InChI key
JERGUCIJOXJXHF-TVWVXWENSA-N
General description
Application
- Enhancement of Steroidogenic Enzyme Assays: The role of protein-protein and protein-membrane interactions in cytochrome P450 function, which is crucial for understanding the enzymatic activities involved in steroid biosynthesis, including those mediated by 17 alpha-Hydroxypregnenolone (Scott EE et al., 2016).
- Modeling Steroid Hormone Biosynthesis: Research explores how ligand and cytochrome b5 modulate the conformation of human cytochrome P450 17A1, a key enzyme in the biosynthesis of neurosteroids from precursors like 17 alpha-Hydroxypregnenolone, providing insights for biochemical steroidogenesis research (Estrada DF et al., 2014).
- Development of ELISA for Steroid Detection: The study demonstrate the covalent coupling of steroids to microwell plates, facilitating the use of 17 alpha-Hydroxypregnenolone in competitive enzyme-linked immunosorbent assays (ELISA) for steroid hormone precursor detection and quantification in biochemical assays (Yonezawa S et al., 1993).
Legal Information
related product
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
wgk_germany
WGK 1
flash_point_f
closed cup
flash_point_c
closed cup
Certificates of Analysis (COA)
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