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N-906

Supelco

Nitrazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15H11N3O3
CAS Number:
146-22-5
Molecular Weight:
281.27
EC Number:
200-835-2
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)

InChI key

KJONHKAYOJNZEC-UHFFFAOYSA-N

General description

A certified solution standard suitable for use as starting material in calibrators and controls of nitrazepam for LC/MS or GC/MS testing methods. Nitrazepam is a benzodiazepine sold as a treatment for severe insomnia. This drug is marketed under the trade names Mogadon, Nitrados, and Somnite.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Description
Pricing

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

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Masatomo Suetsugi et al.
Progress in neuro-psychopharmacology & biological psychiatry, 31(4), 839-847 (2007-03-03)
The first-night effect is a well-known phenomenon that is considered to result from a subject's lack of adaptation to the unfamiliar environment of a sleep laboratory and to the technical equipment used for polysomnography. The effect has been explored as
Treatment of infantile spasms with sodium valproate followed by benzodiazepines.
Pongsakdi Visudhiphan
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 90(10), 2244-2244 (2007-11-29)
Mihalj Posa et al.
Colloids and surfaces. B, Biointerfaces, 74(1), 84-90 (2009-07-28)
Critical micellear concentrations (CMC) were determined for two novel promoters of membrane permeability-7-monoketocholic acid (7-MKC) and 12-monoketocholic acid (12-MKC), using two non-invasive ((1)H NMR relaxation experiment and conductometry) and two invasive (spectral shift and partition coefficient of the probe molecule)
Mihalj Poša et al.
Colloids and surfaces. B, Biointerfaces, 86(2), 285-291 (2011-05-07)
The formation of mixed micelles built of 7,12-dioxolithocholic and the following hydrophobic bile acids was examined by conductometric method: cholic (C), deoxycholic (D), chenodeoxycholic (CD), 12-oxolithocholic (12-oxoL), 7-oxolithocholic (7-oxoL), ursodeoxycholic (UD) and hiodeoxycholic (HD). Interaction parameter (β) in the studied
A O Străulea et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 113(3), 879-884 (2010-03-03)
The authors present the result of an observational study about the withdrawal syndrome in benzodiazepine dependence, and the aspect of identifying withdrawal symptoms, effective communication with the patient and the structure of withdrawal programmes. The study included a number of
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