MilliporeSigma

1.00130

SAFC

Benzoic acid

powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, E 210

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Synonym(s):
Benzoic acid, Phenylformic acid, Benzene carboxylic acid
Empirical Formula (Hill Notation):
C7H6O2
CAS Number:
Molecular Weight:
122.12
E Number:
E210
EC Index Number:
200-618-2

Agency

BP
Ph. Eur.
USP

Quality Level

vapor pressure

0.001 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

Assay

99.5-100.5% substance (anhydrous) basis (acidimetric)

form

powder
solid

autoignition temp.

570 °C

quality

E 210

technique(s)

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

pH

2.5-3.5 (20 °C in H2O, saturated solution)

bp

249 °C/1013 hPa

mp

121-123 °C

transition temp

flash point 121 °C

solubility

water: 2.9 g/L at 25 °C

density

1.321 g/cm3 at 20 °C

anion traces

sulfate (SO42-): ≤0.02%

cation traces

As: ≤1 ppm
Cd: ≤10 ppm
Cr: ≤2.5 ppm
Cu: ≤10 ppm
Hg: ≤1 ppm
Mn: ≤25 ppm
Ni: ≤2 ppm
Pb: ≤2 ppm
Zn: ≤10 ppm

application(s)

liquid formulation
pharmaceutical
semi-solid formulation

storage temp.

15-25°C

InChI

1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

InChI key

WPYMKLBDIGXBTP-UHFFFAOYSA-N

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This Item
1.018061.002631.00713
Benzoic acid powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, E 210

SAFC

1.00130

Benzoic acid

Benzyl benzoate EMPROVE® EXPERT, Ph. Eur., BP, USP

SAFC

1.01806

Benzyl benzoate

Formic acid 98-100%, EMPROVE® ESSENTIAL

SAFC

1.00263

Formic acid

Sulfuric acid 95-98%, EMPROVE® ESSENTIAL, Ph. Eur., BP, JPE, NF

SAFC

1.00713

Sulfuric acid

vapor pressure

0.001 hPa ( 20 °C)

vapor pressure

<0.1 hPa ( 25 °C)

vapor pressure

44.8 mmHg ( 20 °C)

vapor pressure

0.0001 hPa ( 20 °C), 1 mmHg ( 146 °C)

assay

99.5-100.5% substance (anhydrous) basis (acidimetric)

assay

-

assay

≥98% (alkalimetric)

assay

95-97% (alkalimetric)

form

powder, solid

form

liquid

form

liquid

form

liquid

pH

2.5-3.5 (20 °C in H2O, saturated solution)

pH

-

pH

2.2 (20 °C, 10 g/L in H2O)

pH

0.3 (25 °C, 49 g/L in H2O)

bp

249 °C/1013 hPa

bp

324 °C/1013 hPa

bp

100-101 °C (lit.), 101 °C/1013 hPa

bp

~290 °C (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Benzoic acid is typically used as a preservative in pharmaceutical formulations and cosmetics due to its antimicrobial characteristics. It is also used as an additive for the preservation of food.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

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