1.09623

Ethyl acetate

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(s): Ethyl ethanoate, Acetic ester, Ethyl ester, EtOAc
• Linear Formula: CH₃COOC₂H₅
• CAS Number: 141-78-6
• Molecular Weight: 88.11
• Beilstein/REAXYS Number: 506104
• MDL number: MFCD00009171
• UNSPSC Code: 12191502
• EC Index Number: 205-500-4
• NACRES: NA.05

Properties

• grade: ACS reagent; for analytical purposes; for extraction; reagent grade
• Quality Level: 300
• agency: reag. ISO; reag. Ph. Eur.
• vapor density: 3 (20 °C, vs air)
• vapor pressure: 73 mmHg ( 20 °C)
• product line: EMSURE^®
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 801 °F
• potency: 5620 mg/kg LD₅₀, oral (Rat); >18000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 2.2-11.5 %, 38 °F
• impurities: ≤0.0008 meq/g Titrable acid; ≤0.05% Water; ≤0.1% Ethanol (GC); ≤0.1% Methanol (GC); ≤0.1% Methyl acetate (GC)
• evapn. residue: ≤0.001%
• color: clearAPHA: ≤10
• refractive index: n20/D 1.3720 (lit.)
• bp: 76.5-77.5 °C (lit.)
• mp: −84 °C (lit.)
• transition temp: flash point -4 °C
• solubility: 85.3 g/L
• density: 0.902 g/mL at 25 °C (lit.)
• cation traces: Al: ≤500 ng/g; B: ≤20 ng/g; Ba: ≤100 ng/g; Ca: ≤500 ng/g; Cd: ≤50 ng/g; Co: ≤20 ng/g; Cr: ≤20 ng/g; Cu: ≤20 ng/g; Fe: ≤100 ng/g; Mg: ≤100 ng/g; Mn: ≤20 ng/g; Ni: ≤20 ng/g; Pb: ≤100 ng/g; Sn: ≤100 ng/g; Zn: ≤100 ng/g
• SMILES string: CCOC(C)=O
• application(s): environmental; food and beverages; industrial qc; pharmaceutical; sample preparation
• format: neat
• storage temp.: 2-30°C
• InChI: 1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
• InChI key: XEKOWRVHYACXOJ-UHFFFAOYSA-N

Description

General description

EMSURE grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE provides worldwide best and most extensive product specifications. We declare our EMSURE range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.

Application

• Investigating the anti-growth, anti-resistance, and anti-virulence activities of Schoepfia schreberi J.F.Gmel. against the superbug Acinetobacter baumannii.: This study evaluates the effectiveness of plant extracts, possibly involving ethyl acetate as a solvent or extractant, in combating bacterial resistance and virulence, presenting potential applications in analytical methodologies focused on bioactivity assessment (Uc-Cachón et al., 2024).


• Attractant and repellent properties of Senna didymobotrya plant extracts to Amblyomma variegatum and Rhipicephalus appendiculatus.: The research explores natural extract′s efficacy, utilizing ethyl acetate in the extraction process, as eco-friendly pest management solutions, relevant in developing analytical techniques for environmental and agricultural applications (Kinyua et al., 2024).


• Antioxidant activity of Sophora exigua and liposome development of its powerful extract.: This paper discusses the antioxidant properties of plant extracts, with implications for ethyl acetate use in extraction and stabilization processes in pharmaceutical and food industries, enhancing analytical methods for antioxidant capacity measurement (Rodwattanagul et al., 2024).


• In vitro ovicidal and larvicidal activity of a hydroalcoholic extract and its fractions from Cyrtocarpa procera fruits on Haemonchus contortus.: The study investigates ethyl acetate′s role in isolating bioactive compounds with potential applications in the analysis of antiparasitic agents, relevant to both medical and veterinary parasitology (De Jesús-Martínez et al., 2024).


• Antagonistic actions of Paucibacter aquatile B51 and its lasso peptide paucinodin toward cyanobacterial bloom-forming Microcystis aeruginosa PCC7806.: This research focuses on microbial interactions and the role of ethyl acetate in the extraction of peptides, applicable in the analytical examination of microbial ecology and environmental safety (Cha et al., 2024).

Analysis Note

Purity (GC): ≥ 99.5 %
Identity (IR): conforms
Appearance: clear
Color: ≤ 10 Hazen
Titrable acid: ≤ 0.0008 meq/g
Density (d 20 °C/20 °C): 0.901 - 0.904
Boiling point: 76 - 78 °C
Readily carbonizable substances: conforms
Ethanol (GC): ≤ 0.1 %
Methanol (GC): ≤ 0.1 %
Methyl acetate (GC): ≤ 0.1 %
Al (Aluminium): ≤ 500 ng/g
B (Boron): ≤ 20 ng/g
Ba (Barium): ≤ 100 ng/g
Ca (Calcium): ≤ 500 ng/g
Cd (Cadmium): ≤ 50 ng/g
Co (Cobalt): ≤ 20 ng/g
Cr (Chromium): ≤ 20 ng/g
Cu (Copper): ≤ 20 ng/g
Fe (Iron): ≤ 100 ng/g
Mg (Magnesium): ≤ 100 ng/g
Mn (Manganese): ≤ 20 ng/g
Ni (Nickel): ≤ 20 ng/g
Pb (Lead): ≤ 100 ng/g
Sn (Tin): ≤ 100 ng/g
Zn (Zinc): ≤ 100 ng/g
Evaporation residue: ≤ 0.001 %
Water: ≤ 0.05 %

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319,H336
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 24.8 °F - closed cup
• flash_point_c: -4 °C - closed cup