MilliporeSigma

1.11037

SAFC

tri-Sodium citrate

anhydrous, EMPROVE® ESSENTIAL, USP, FCC, E 331

Synonym(s):
tri-Sodium citrate
Empirical Formula (Hill Notation):
C6H5Na3O7
CAS Number:
Molecular Weight:
258.07
MDL number:
E Number:
E331
EC Index Number:
200-675-3

Agency

USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

7.5-9.0 (20 °C, 10 g/L in H2O)

mp

150 °C (decomposition)

solubility

425 g/L

density

1.76 g/cm3 at 18 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

InChI

1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3

InChI key

HRXKRNGNAMMEHJ-UHFFFAOYSA-K

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This Item
1.064471.064461.06432
tri-Sodium citrate anhydrous, EMPROVE® ESSENTIAL, USP, FCC, E 331

SAFC

1.11037

tri-Sodium citrate

tri-Sodium citrate dihydrate EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

SAFC

1.06447

tri-Sodium citrate dihydrate

tri-Sodium citrate dihydrate powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, E 331

SAFC

1.06446

tri-Sodium citrate dihydrate

tri-Sodium citrate dihydrate crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, E 331

SAFC

1.06432

tri-Sodium citrate dihydrate

form

solid

form

solid

form

powder, solid

form

crystalline, solid

pH

7.5-9.0 (20 °C, 10 g/L in H2O)

pH

7.5-9.0 (25 °C, 50 g/L in H2O)

pH

7.5-9.0 (25 °C, 50 g/L in H2O)

pH

7.5-9.0 (25 °C, 50 g/L in H2O)

mp

150 °C (decomposition)

mp

150 °C (anhydrous substance), >300 °C (lit.)

mp

150 °C (anhydrous substance), >300 °C (lit.)

mp

150 °C (anhydrous substance), >300 °C (lit.)

solubility

425 g/L

solubility

-

solubility

-

solubility

-

density

1.76 g/cm3 at 18 °C

density

-

density

-

density

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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