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444212

Sigma-Aldrich

MMP-2 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10⁵ M⁻¹s⁻¹).

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Synonym(s):
MMP-2 Substrate, Fluorogenic
Empirical Formula (Hill Notation):
C49H68N14O15
Molecular Weight:
1093.15

Quality Level

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

yellow

solubility

DMSO: 10 mg/mL

fluorescence

λex ~325 nm
λem ~393 nm

shipped in

ambient

storage temp.

−20°C

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MMP-1/MMP-9 Substrate, Fluorogenic

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manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

color

yellow

color

yellow

color

yellow

color

red

storage condition

OK to freeze, protect from light, desiccated

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

General description

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1).
A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1; excitation maximum: ~325 nm; emission maximum: ~393 nm).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A quenched fluorescence substrate for MMP-2 (gelatinase A)
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

MCA-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂[Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]

Other Notes

Murphy, G., et al. 1994. J. Biol. Chem. 269, 6632.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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