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4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.

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Synonym(s):
4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide, 4-Methylumbelliferyl-2-acetamido-2-deoxy-α-D-glucopyranoside
Empirical Formula (Hill Notation):
C18H21NO8
CAS Number:
Molecular Weight:
379.36

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

impurities

<0.05% 4-methylumbelliferone
<0.2% β-anomer

color

white

solubility

DMF: soluble
DMSO: soluble

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18+/m1/s1

InChI key

QCTHLCFVVACBSA-FGTAOJJYSA-N

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This Item
69591M2133M9659
manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

10-30°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMF: soluble, DMSO: soluble

solubility

DMSO: 50 mg/mL, clear, colorless to faintly yellow

solubility

DMF: 20 mg/mL, clear, colorless to faintly yellow

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

storage condition

OK to freeze, protect from light, desiccated

storage condition

-

storage condition

-

storage condition

-

General description

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo B syndrome. Excitation maximum: 360 nm; emission maximum: 440 nm.
Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Analysis Note

single spot by TLC

Other Notes

Marsh, J., and Fensom, A.H. 1985. Clin. Genet.27, 258.
Chow, P., and Weissmann, B. 1981. Carbohydr. Res. 96, 87.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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