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4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes.

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Synonym(s):
4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, 4-Methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside, K
Empirical Formula (Hill Notation):
C18H20NO11S · K
Molecular Weight:
497.51

Quality Level

assay

≥98% (HPLC)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

white

solubility

water: 20 mg/mL

fluorescence

λex 360 nm
λem 440 nm

shipped in

ambient

storage temp.

−20°C

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This Item
M2133M7133M6018
manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥99% (HPLC)

assay

≥98.00% (TLC)

solubility

water: 20 mg/mL

solubility

DMF: 20 mg/mL, clear, colorless to faintly yellow

solubility

water: 5 mg/mL, clear, colorless

solubility

water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

storage condition

OK to freeze, protect from light, desiccated

storage condition

-

storage condition

-

storage condition

-

General description

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes.
Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes. Excitation maximum: ~360 nm; emission maximum: ~440 nm.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Greloner, E.E., and Wenger, D.A. 1987. Prenat. Diag. 7, 419.
Bayleran, J., et al. 1984. Clin. Chim. Acta143, 73.
Inui, K., and Wenger, D.A. 1984. Clin. Genet.25, 93.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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