538903

Prostaglandin E₁

Activates adenylate cyclase activity via a G-protein coupled receptor.

• Synonym(s): Prostaglandin E₁, PGE₁
• Empirical Formula (Hill Notation): C₂₀H₃₄O₅
• CAS Number: 745-65-3
• Molecular Weight: 354.48
• MDL number: MFCD00077860
• UNSPSC Code: 12352211
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white to off-white
• solubility: ethanol: 50 mg/mL; methanol: 50 mg/mL; DMSO: soluble
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
• InChI key: GMVPRGQOIOIIMI-DWKJAMRDSA-N

Description

General description

Activates adenylate cyclase activity via a G-protein coupled receptor.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Activates adenylate cyclase activity

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 1 month at -20°C.

Other Notes

Ammer, H. and Schulz, R. 1993. Mol. Pharmacol. 43, 556.
Rubin, D. and Laposata, M. 1991. J. Biol. Chem.266, 23618.
Kurstjens, N.P., et al. 1990. Biochem. Biophys. Res. Commun.167, 1162.
Krakauer, K.A., et al. 1986. Prostaglandins32, 301.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable