Skip to Content
MilliporeSigma

8.17002

SAFC

Polyethylene glycol

300, EMPROVE® EXPERT, Ph. Eur., NF

Pharma Manufacturing

Synonym(s):

Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 300, PEG

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
13111021
EC Index Number:
500-038-2

agency

NF
Ph. Eur.

Quality Level

vapor pressure

<0.1 hPa ( 20 °C)

product line

EMPROVE® EXPERT

form

liquid

autoignition temp.

370 °C

mol wt

average Mn 300

pH

4-7 (20 °C, 100 g/L in H2O)

bp

>220 °C/1013 hPa (decomposes)

mp

-15--10 °C

transition temp

flash point 220 °C

density

1.13 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solubility enhancement

Storage temp.

no temp limit

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Inchi Key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

Related Content

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service