MilliporeSigma

8.17006

SAFC

Polyethylene glycol

4000, powder, EMPROVE® ESSENTIAL, Ph. Eur.

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Synonym(s):
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 4000, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
EC Index Number:
500-038-2

agency

Ph. Eur.

Quality Level

vapor pressure

<0.01 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

form

powder
solid

autoignition temp.

>320 °C (DIN 51794)

mol wt

average Mn 4000

technique(s)

API processing | nano-milling: suitable

pH

5-7 (20 °C, 100 g/L in H2O)

mp

53-58 °C

transition temp

flash point 270 °C

density

1.2 g/cm3 at 20 °C

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

shipped in

ambient

storage temp.

15-25°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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1 of 4

This Item
PHR28928.07490PHR2891
vibrant-m

8.17006

Polyethylene glycol

vibrant-m

PHR2892

Polyethylene Glycol 4000

vibrant-m

8.07490

Polyethylene glycol

vibrant-m

PHR2891

Polyethylene Glycol 400

Quality Level

500

Quality Level

300

Quality Level

200

Quality Level

300

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

density

1.2 g/cm3 at 20 °C

density

-

density

1.2 g/cm3 at 20 °C

density

-

storage temp.

15-25°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

mol wt

average Mn 4000

mol wt

-

mol wt

-

mol wt

-

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup


Certificates of Analysis (COA)

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-
25G
Pack Size/Quantity

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705578-5MG-PW

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MMYOMAG-74K-13

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Articles

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service