8.20551

1,2-Epoxybutane

for synthesis

• Synonym(s): 1,2-Epoxybutane, Ethyloxirane, 1,2-Butylene oxide
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 106-88-7
• Molecular Weight: 72.11
• MDL number: MFCD00005153
• UNSPSC Code: 12352005
• EC Index Number: 203-438-2
• NACRES: NA.22

Properties

• vapor pressure: 1005 hPa ( 63 °C)
• Quality Level: 200
• assay: ≥99.0% (GC)
• form: liquid
• autoignition temp.: 370 °C
• potency: 500 mg/kg LD₅₀, oral (Rat); 1743 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.7-19 % (v/v)
• pH: 7 (20 °C, 50 g/L in H₂O)
• bp: 63 °C/1013 hPa
• mp: -130 °C
• transition temp: flash point -26 °C
• solubility: 86.8 g/L
• density: 0.83 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C4H8O/c1-2-4-3-5-4/h4H,2-3H2,1H3
• InChI key: RBACIKXCRWGCBB-UHFFFAOYSA-N

Description

Application

• Efficient catalysis of CO₂ cycloaddition: 1,2-Epoxybutane is utilized in the synthesis of hydroxy-rich covalent organic frameworks, proving effective in catalyzing CO₂ cycloaddition. This application supports environmental sustainability efforts through the conversion of carbon dioxide into useful compounds (Pang et al., 2023).
• Strain-release reagent synthesis: Highlighting its versatility as a chemical intermediate, 1,2-Epoxybutane is used in one-pot syntheses of strain-release reagents from methyl sulfones. This research opens new avenues in synthetic chemistry for creating novel organic compounds efficiently (Jung and Lindsay, 2022).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.830 - 0.831
Identity (IR): passes test

Safety Information

• pictograms: GHS02,GHS07,GHS08
• signalword: Danger
• hcodes: H225 - H302 + H312 + H332 - H315 - H319 - H335 - H351
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 5.0 °F - closed cup
• flash_point_c: -15 °C - closed cup