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AP510S

Sigma-Aldrich

Sheep Anti-Rabbit IgG Antibody, Cy5 conjugate

from sheep, CY5 conjugate

Synonym(s):

Rabbit immunoglobulin G, Rabbit immunoglobulin gamma

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.45

biological source

sheep

Quality Level

conjugate

CY5 conjugate

antibody form

purified antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

rabbit

technique(s)

immunocytochemistry: suitable

shipped in

wet ice

target post-translational modification

unmodified

Related Categories

General description

Immunoglobulin G (IgG) is part of the family of glycoprotein immunoglobulins which stage immune responses against pathogenic organisms. IgG contributes to the immune response by mobilizing innate immune effector cells and inducing and pro-inflammatory responses. Such proinflammatory responses are mediated by Fcg receptors which interact with sialylated Fc fragments on IgG molecules.

Specificity

This antibody reacts with rabbit IgG and rabbit IgG (Fc). Minimal cross-reactivity detected with Human IgG and Rabbit IgM; little to no cross-reactivity detected with Mouse IgG, Rat IgG, Chicken IgY, Guinea Pig IgG, and Hamster IgG.

Immunogen

Rabbit IgG

Application

Immunocytochemistry Analysis: Performance of this secondary antibody is validated (1.25 µg/mL) by indirect fluorescent labeling of H3K27me3 in HUVECs following a rabbit polyclonal parimary antibody (Cat. No. 07-449) in immunocytochemistry application.
Research Category
Secondary & Control Antibodies
Research Sub Category
Whole Immunoglobulin Secondary Antibodies
This Sheep Anti-Rabbit IgG Antibody, Cy5 conjugate is validated for use in Immunocytochemistry for the detection of Sheep Rabbit IgG.

Quality

Evaluated by Immunocytochemistry in NIH/3T3 cells.

Immunocytochemistry Analysis: Performance of this secondary antibody is validated (1.25 µg/mL) by indirect fluorescent labeling of H3K27me3 in NIH/3T3 following a rabbit polyclonal parimary antibody (Cat. No. 07-449) in immunocytochemistry application.

Physical form

Protein A purified
Purified sheep antibody Conjugate in PBS with 15 mg/ml BSA and 0.1 % sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joshua Miguel C Danac et al.
Scientific reports, 11(1), 9021-9021 (2021-04-29)
Circular RNAs have emerged as functional regulatory molecules whose aberrant expression has been linked to diverse pathophysiological processes. Here, we report that circPVT1 interferes with let-7 binding to NRAS, confirming this axis as one route by which circPVT1 can instigate

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