AX0156

Acetonitrile

≥99.9% (GC), suitable for LC/MS, OmniSolv^®

• Synonym(s): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
• Linear Formula: CH₃CN
• CAS Number: 75-05-8
• Molecular Weight: 41.05
• Beilstein/REAXYS Number: 741857
• MDL number: MFCD00001878
• UNSPSC Code: 12352117
• EC Index Number: 200-835-2

Properties

• product name: Acetonitrile, OmniSolv^® LC-MS
• agency: suitable for ASTM^® 7968; suitable for ASTM^® 7979; suitable for DIN 38407-42; suitable for EPA 1633; suitable for EPA 8327; suitable for GB 31604.35-2016; suitable for GB 5009.253-2016; suitable for ISO 21675 2019
• Quality Level: 100
• reg. compliance: suitable for FDA C-010.02
• vapor density: 1.41 (vs air)
• vapor pressure: 72.8 mmHg ( 20 °C); 97 hPa ( 20 °C)
• product line: OmniSolv^®
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 973 °F
• expl. lim.: 16 %
• technique(s): LC/MS: suitable
• impurities: ≤0.02% Water (H₂O); ≤0.5 μeq/g Titrable base; ≤1 μeq/g Titrable acid; ≤50 ppb p-nitrophenol (LC/MS); ≤50 ppb reserpine (LC/MS)
• evapn. residue: ≤1 ppm
• color: APHA: ≤10
• refractive index: n20/D 1.344 (lit.)
• bp: 81-82 °C (lit.)
• mp: −45 °C (lit.)
• transition temp: flash point 2 °C
• density: 0.786 g/mL at 25 °C (lit.)
• UV cutoff: ≤190 nm
• UV absorption: λ: 200 nm A_max: ≤0.1; λ: 210 nm A_max: ≤0.04; λ: 220 nm A_max: ≤0.02; λ: 230 nm A_max: ≤0.01; λ: 240 nm A_max: ≤0.01; λ: 250 nm A_max: ≤0.01; λ: 270 nm A_max: ≤0.01; λ: 400-280 nm A_max: ≤0.005
• SMILES string: CC#N
• format: neat
• shipped in: ambient
• storage temp.: room temp
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

General description

Acetonitrile is a water-soluble polar organic solvent with exceptional solubilizing power, unique chromatographic properties, and ideal spectroscopic characteristics.

Application

Acetonitrile is used as a:

• Mobile phase solvent in reversed-phase chromatography.
• Rinsing solvent for Solid-phase extraction (SPE) column.

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Assay (GC)99.9% minColor (APHA)10APHA maxEvaporation residue1ppm maxFiltered through 0.2 µm filterTo pass testFluorescence as quinine at 254 nm1ppb maxFluorescence as quinine at 365 nm1ppb maxFormClear liquidGradient at 210 nm2mAU maxGradient at 254 nm0.3mAU maxIdentity (IR-spectrum)ConformsLC-MS purity, ESI(+), as reserpine50ppb maxLC-MS purity, ESI(-), as p-nitrophenol50ppb maxMetals, suitable for LC/MSTo pass testTitrable acid1µeq/g maxTitrable base0.5µeq/g maxUV Abs. at 200 nm0.1AU maxUV Abs. at 210 nm0.04AU maxUV Abs. at 220 nm0.02AU maxUV Abs. at 230 nm0.01AU maxUV Abs. at 240 nm0.01AU maxUV Abs. at 250 nm0.01AU maxUV Abs. at 270 nm0.01AU maxUV Abs. at 400-280 nm0.005AU maxUV Cut-off190nm maxWater (H2O)0.02% max

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 35.6 °F - closed cup
• flash_point_c: 2.0 °C - closed cup