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Anti-Cathepsin D (Ab-1) Mouse mAb (BC011)

liquid, clone BC011, Calbiochem®

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biological source


Quality Level

antibody form

purified antibody

antibody product type

primary antibodies


BC011, monoclonal




≤0.1% sodium azide as preservative

species reactivity




storage condition

do not freeze



shipped in

wet ice

storage temp.


target post-translational modification


Gene Information

human ... CTSD(1509)

General description

Anti-Cathepsin D (Ab-1), mouse monoclonal, clone BC011, recognizes latent and mature form and the ~34 kDa subunit in breast carcinoma tissue extracts. It is validated for WB and for paraffin sections.
Purified mouse monoclonal antibody generated by immunizing CB6F1 mice with the specified immunogen and fusing splenocytes with SP2/0 cells. Recognizes the ~52 kDa pro-cathespin D, the ~48 kDa mature cathepsin D, and the ~34 kDa subunit of cathespin D.
Recognizes the ~52 kDa latent form, the ~48 kDa mature form, and the ~34 kDa subunit of cathepsin D in breast carcinoma tissue extracts.


mature, human cathepsin D


Immunoblotting (1 µg/ml)

Paraffin Sections (5 µg/ml, trypsin pre-treatment required)


Please refer to vial label for lot-specific concentration.


Toxicity: Standard Handling (A)

Other Notes

Does not detect the ~14 kDa subunit of cathespin D, nor will it detect cathespins B or L. Cathepsins are secreted and accumulate in conditioned tissue culture media and can be detected by immunoblotting from this source. Some cell extracts do not contain sufficient cathepsin for detection by immunoblotting. Antibody should be titrated for optimal results in individual systems.
Rochefort, H. 1992. Eur. J. Cancer.28A, 1780.
Rochefort, H. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1(2), 153.
Westly, B. and Rochefort, H. 1980. Cell20, 352.
Barrett, A.J. 1977. in Proteinases in Mammalian Cells and Tissues, ed. Barret, A.J. (North Holland, New York), pp. 209.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids




Not applicable


Not applicable

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Cecilia Bivik et al.
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F Gong et al.
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Jingyi Li et al.
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