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Aervent® 0.2 µm, Opticap® XL Capsule

Opticap® XL 10, inlet connection diam. 1.5 in., pore size 0.2 μm, cartridge nominal length 10 in. (25 cm)

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Aervent KTGR Opticap XL10 Capsule


polypropylene housing
polypropylene support
polypropylene vent cap
silicone seal

Quality Level



sterilization compatibility

autoclavable compatible

product line

Opticap® XL 10






≤24 mL/min nitrogen diffusion at 970 mbar (14 psig) and 23 °C (in 70/30% IPA/water)
1.0 bar max. differential pressure (15 psid) at 80 °C (Forward)
1.0 bar max. inlet pressure (15 psi) at 80 °C (Forward)
2.8 bar max. inlet pressure (40 psi) at 60 °C (Forward)
25 °C max. inlet temp.
4.1 bar max. differential pressure (60 psid) (Reverse; intermittent)
4.1 bar max. inlet pressure (60 psi) (Reverse; Intermittent)
5.5 bar max. differential pressure (80 psid) at 25 °C (Forward)
5.5 bar max. inlet pressure (80 psi) at 25 °C (Forward)
80 psig max. inlet pressure


gas filtration: suitable


33.5 cm (13.2 in.)


4.2 in.

cartridge nominal length

10 in. (25 cm)


10.7 cm (4.2 in.)

filtration area

0.65 m2

inlet connection diam.

1.5 in.

inlet to outlet W

33.5 cm (13.2 in.)

outlet connection diam.

1.5 in.


<0.25 EU/mL USP bacterial endotoxins (LAL test, aqueous extraction)

gravimetric extractables

≤45 mg/cartridge



pore size

0.2 μm pore size


sample type gas

bubble point

≥1100 mbar (16 psig), nitrogen with 70/30% IPA/water at 23 °C


1/4 in. drain/vent hose barb (with double O-ring Seal)
inlet sanitary flange
outlet sanitary flange
(38 mm (1 1/2 in.) Sanitary Flange Inlet and Outlet)

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General description

Device Configuration: Capsule

Features and Benefits

Rated for aerosol retention of a total challenge of 108–1010 plaque forming units of ΦX-174 virus particles at 85 Nm3/h (50 SCFM) per cartridge.


Double Easy-Open bag


Retains Brevundimonas diminuta liquid aerosol for 21 days at a minimum challenge of 10⁷ CFU/cm²


Replaces: SN2M027A6

Preparation Note

Sterilization Method
30 autoclave cycles of 30 min @ 135 °C
This product was manufactured with a PTFE membrane which meets the criteria for a "non-fiber releasing" filter as defined in 21 CFR 210.3 (b) (6).

Analysis Note

Bacterial Retention
Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology.
Gravimetric Extractables: after 24 hours in a 70/30% IPA/water mixture at controlled room temperature
HydroCorr: ≤0.75 mL/min @ 2.6 bar (38 psig) per sample

Other Notes

Directions for Use
  • Organism Retention: Microorganism
  • Mode of Action: Filtration (size exclusion)
  • Application: BioProcessing
  • Intended Use: Reduction or removal of microorganism/bioburden
  • Instructions for Use: Please refer Steam Sterilization & Integrity Testing Procedures guide and first page of Visual Inspection Guide
  • Storage Statement: Store in dry location
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.

Legal Information

AERVENT is a registered trademark of Merck KGaA, Darmstadt, Germany
ASTM is a registered trademark of American Society for Testing and Materials
OPTICAP is a registered trademark of Merck KGaA, Darmstadt, Germany


EMD Millipore Corporation certifies that this product complies with the European Pressure Equipment Directive, 2014/68/EU of 15 May 2014. This product has been classified under Article 4 § 3 of the Directive 2014/68/EU. It has been designed and manufactured in accordance with sound engineering practice to ensure safe use. In compliance with Article 4 § 3 of the Directive 2014/68/EU, this product does not bear the CE mark.

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