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MAB317

Sigma-Aldrich

Anti-Calcitonin Gene Related Peptide Antibody, α hCGRP a.a. 28-37, clone CD8

clone CD8, Chemicon®, from mouse

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eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

CD8, monoclonal

species reactivity

guinea pig, human

should not react with

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CALCA(796)

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This Item
AB15360C7113HPA064453
Gene Information

human ... CALCA(796)

Gene Information

human ... CALCA(796)

Gene Information

human ... CALCA(796)
rat ... Calca(24241)

Gene Information

human ... CALCA(796)

species reactivity

guinea pig, human

species reactivity

rat

species reactivity

rat, human, canine

species reactivity

human

antibody form

purified antibody

antibody form

serum

antibody form

purified from hybridoma cell culture

antibody form

affinity isolated antibody

clone

CD8, monoclonal

clone

polyclonal

clone

4901, monoclonal

clone

polyclonal

UniProt accession no.

P01258

UniProt accession no.

P01258, P10092

UniProt accession no.

P01258

UniProt accession no.

-

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Specificity

Highly specific for CGRP and does not cross-react with other amino acids.

Immunogen

A terminal fragment of hCGRP coupled to BSA with glutaraldehyde.
Epitope: alpha hCGRP a.a. 28-37

Application

Anti-Calcitonin Gene Related Peptide Antibody, α hCGRP a.a. 28-37, clone CD8 is an antibody against Calcitonin Gene Related Peptide for use in ELISA, IH.
Immunohistochemistry at 1:200-1:400. Antibody not reactive on formalin fixed tissues. 4% PFA frozen tissues preferred. Immersion (2 hours) or perfused (pH7.4); Blocking in PBS with 3% BSA or NGS containing 0.1% triton X-100 is advised. Primary antibody should be diluted only in PBS with no detergent or blocking compounds.

ELISA: against BSA-conjugated alpha CGRP peptide.



Optimal working dilutions to be determined by end user.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors

Physical form

Format: Purified

Storage and Stability

Maintain refrigerated at 2-8°C for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Mast cells express the substance P (SP) neurokinin 1 receptor and the calcitonin gene-related peptide (CGRP) receptor in guinea pig and human small intestine. Enzyme-linked immunoassay showed that activation of intramural afferents by antidromic electrical stimulation or by capsaicin released

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