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MAB4315

Sigma-Aldrich

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon®

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eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

STRO-1, monoclonal

species reactivity

human, primate

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunofluorescence: suitable

input

sample type mesenchymal stem cell(s)

isotype

IgM

shipped in

dry ice

target post-translational modification

unmodified

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This Item
MAB4381FCMAB117PSAB4701067
clone

STRO-1, monoclonal

clone

TRA-1-81, monoclonal

clone

MC-480, monoclonal

clone

SY11B5, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

ascites fluid

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

isotype

IgM

isotype

IgM

isotype

IgM

isotype

-

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General description

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Specificity

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Immunogen

CD34+ bone marrow cells

Application

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Analysis Note

Control
Bone marrow cultures

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Byung Cheol Kim et al.
Journal of biomedical research, 33(2), 122-130 (2019-04-24)
Despite their potential applications in future regenerative medicine, periodontal ligament stem cells (PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining stemness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from
Jeong Seok Lee et al.
Journal of cell communication and signaling, 12(4), 661-672 (2018-05-05)
A mussel-inspired polydopamine (PDA), resulting from the oxidative polymerization of dopamine, was reported to be an attractive substrate for advancing biomaterial applications. Thus, this study determined the osteoconductive/osteoinductive properties of titanium (Ti) surfaces coated with PDA and the facilitation of
Jeong Seok Lee et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34(5), 1824-1834 (2014-12-17)
Mussel-inspired polydopamine (PDA) is known to be an effective bioadhesive and bioactive material for controlling stem cell fate, which is important in stem cell-based regenerative medicine; however, the effect of PDA on osteogenic differentiation of periodontal ligament stem cells (PDLSCs)
Maha I Abdelfattah et al.
Open access Macedonian journal of medical sciences, 4(3), 461-467 (2016-10-06)
The aim of this study was to analyze the cytotoxicity of ciprofloxacin (CIP) loaded on chitosan bioactive glass scaffold on human periodontal ligament stem cells (PLSCs) in vitro. PLSCs obtained from human third molars, cultures treated with medium containing 15
Carol Po Ying Lau et al.
International journal of oncology, 42(2), 437-443 (2012-12-12)
Giant cell tumor of bone (GCT) is a destructive neoplasm of uncertain etiology that affects the epiphyseal ends of long bones in young adults. GCT stromal cells (GCTSCs) are the primary neoplastic cells of this tumor and are the only

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Frequently asked questions about mesenchymal stem cells including MSC derivation, expansion, differentiation and allogenic stem cell therapy.

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Information about mesenchyme, specifically mesenchymal stem cell procotols. Step-by-step cell culture protocols for mesenchymal stem cell (MSC) isolation, expansion and differentiation.

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