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MAB8783

Sigma-Aldrich

Anti-SARS Antibody, S Specific, clone 154C

clone 154C, Chemicon®, from mouse

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eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

154C, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
neutralization: suitable
western blot: suitable

shipped in

wet ice

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This Item
MABF3073MABF2789MABF3072
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

species reactivity

human

species reactivity

SARS coronavirus

species reactivity

virus

species reactivity

SARS coronavirus

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

technique(s)

ELISA: suitable, neutralization: suitable, immunofluorescence: suitable, western blot: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable, neutralization: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

ELISA: suitable, neutralization: suitable, western blot: suitable

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General description

Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). Human coronaviruses (HCoVs) were previously only associated with mild diseases. The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein; the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N). It is an enveloped, positive-sense, single-stranded RNA virus.

Specificity

SARS-associated coronavirus (SARS-CoV) S proteins.

Immunogen

Epitope: S Specific

Application

Anti-SARS Antibody, S Specific, clone 154C is suitable for the detection of SARS in:
  • Immunofluorescence
  • ELISA
  • Western Blot
  • Immunoblot
  • Neutralization

Optimal dilutions must be determined by the end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Biochem/physiol Actions

Severe acute respiratory syndrome (SARS) -associated coronavirus′ (SARS-CoV) spike glycoprotein mediates the viral entry by binding to the host cell receptor. SARS spike protein is the target for vaccine development and antibody therapies.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB, 0.25M sodium chloride with 0.1% sodium azide as a preservative

Storage and Stability

Store at 2 to 8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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The nucleocapsid protein of SARS-CoV-2: a target for vaccine development.
Dutta NK, et al.
Journal of virology, 94(13) (2020)
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.
Letko M, et al.
Nature microbiology, 5(4), 562-569 (2020)
The Nucleocapsid Protein of SARS-CoV-2: a Target for Vaccine Development.
Noton K Dutta et al.
Journal of virology, 94(13) (2020-06-18)
An imperative need for research on the role of environmental factors in transmission of novel coronavirus (COVID-19).
Qu G, et al.
Environmental Science & Technology, 57(7), 3730-3732 (2020)
An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19).
Guangbo Qu et al.
Environmental science & technology, 54(7), 3730-3732 (2020-03-24)

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