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MABF930M

Sigma-Aldrich

Anti-TCR Vγ1.1 Antibody, clone 2.11

clone 2.11, from hamster(Armenian)

Synonym(s):

T-cell receptor gamma chain C region C10.5

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$182.00
100 μG
$401.00

$182.00


Estimated to ship onMarch 23, 2025


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25 μG
$182.00
100 μG
$401.00

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

$182.00


Estimated to ship onMarch 23, 2025


Request a Bulk Order

biological source

hamster (Armenian)

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2.11, monoclonal

species reactivity

mouse

packaging

antibody small pack of 25 μg

technique(s)

flow cytometry: suitable
immunoprecipitation (IP): suitable

isotype

IgGκ

UniProt accession no.

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This Item
MAB1962MAB1962ZSAB4700399
species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

clone

MEM 48, monoclonal

clone

P4H9, monoclonal

clone

P4H9, monoclonal

clone

MEM-148, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... ITGB2(3689)

Gene Information

human ... ITGB2(3689)

Gene Information

human ... ITGB2(3689)

Gene Information

human ... ITGB2(3689)

UniProt accession no.

P05107

UniProt accession no.

P05107

UniProt accession no.

P05107

UniProt accession no.

P05107

General description

T cell receptor (TCR) is a single-pass membrane protein that associates with CD3 to form a CD3/TCR complex. It can be a heterodimer of either alpha and beta chains or gamma and delta chains. CD3/RCR complex plays major role in antigen recognition and activation of T cells. The V gamma 1 gene almost exclusively rearranges to the J gamma 4-C gamma 4 gene. V-gamma 1- J gamma 4-C gamma 4 expressing cells form a major population of gamma/delta T cells in thymus and peripheral lymphoid organs in adult mice. However, during early development they are present in lower numbers. This antibody (clone 2.11) recognizes the V gamma 1.1 chain of the heterodimeric gamma/delta T-cell receptor, but does react with TCR alpha/beta bearing cells.

Specificity

Clone 2.11 detects T-cell receptor gamma chain C region C10.5 in lymphocytes.

Immunogen

Irradiated TCR gamma/delta expressing T3 .13.1 hybridoma cells.

Application

Anti-TCR V 1.1, clone 2.11, Cat. No. MABF930, is an armenian hamster monoclonal antibody that detects T-cell receptor gamma chain C region C10.5. and has been tested for use Flow Cytometry, and Immunoprecipitation.
Flow Cytometry Analysis: A representative lot detected TCR V gamma 1.1 in Flow Cytometry applications (Pereira, P., et. al. (1995). J Exp Med. 182(6):1921-30; Pereira, P., et. al. (2004). J Immunol. 173(5):3261-70).

Flow Cytometry Analysis: A 1:500 dilution from a representative lot detected TCR V gamma 1.1 in Lymphocytes isolated from TcrdH2BeGFP reporter mice (Courtesy of Dr rer. nat. Inga Sandrock, Hannover Medical School, Germany).

Immunoprecipitation Analysis: A representative lot detected TCR V gamma 1.1 in Immunoprecipitation applications (Pereira, P., et. al. (1995). J Exp Med. 182(6):1921-30).
Research Category
Inflammation & Immunology

Quality

Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG.

Target description

19.10 kDa calculated.

Physical form

Format: Purified
Protein G purified
Purified armenian hamster monoclonal antibody IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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