MilliporeSigma

P3B030D10

Millipore

Pellicon® 3 Cassette with Biomax® Membrane

30 kDa, D screen, 1.14 m2

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Synonym(s):
Pellicon® 3 Cassette with Biomax 30 kDa Membrane, D screen, 1.14 m2
eCl@ss:
32031623

material

TPE seal
polyethersulfone membrane
polypropylene housing
polypropylene screen
stainless steel cap (for end; polypropylene-encapsulated)

Quality Level

manufacturer/tradename

Pellicon®

storage condition

do not freeze

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours)
4-6 L/min-m2 recirculation rate
4-8 L/min-m2 flow rate
40 psi max. transmembrane pressure at 4-50 °C
6.9 bar max. inlet pressure (100 psi)
80 psi max. transmembrane pressure at 4-40 °C

technique(s)

tangential flow filtration (TFF): suitable
ultrafiltration: suitable

H

4.2 cm (1.67 in.)

L

20.6 cm (8.1 in.)

W

17.8 cm (7 in.)

filtration area

1.14 m2

size

229 mL , Volume (feed)
88 mL , Volume (permeate)

gravimetric extractables

≤1500 mg/m2

matrix

Biomax®

pore size

(30 kDa)

pH

1-14

storage temp.

2-8°C

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This Item
P3B030A10P3B030A00P3B030A05
filtration area

1.14 m2

filtration area

-

filtration area

88 cm2

filtration area

-

material

TPE seal, polypropylene housing, stainless steel cap (for end; polypropylene-encapsulated), polyethersulfone membrane, polypropylene screen

material

TPE seal, polyethersulfone , polypropylene screen, stainless steel cap (for end; polypropylene-encapsulated)

material

TPE seal, polyethersulfone membrane (void free), polypropylene , polypropylene cap (for end), polypropylene screen

material

TPE seal, polyethersulfone , polypropylene screen, stainless steel cap (for end; polypropylene-encapsulated)

matrix

Biomax®

matrix

Biomax® (Membrane)

matrix

Biomax® (Membrane)

matrix

Biomax® (Membrane)

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-8 L/min-m2 flow rate, 6.9 bar max. inlet pressure (100 psi), 4-6 L/min-m2 recirculation rate, 80 psi max. transmembrane pressure at 4-40 °C, 40 psi max. transmembrane pressure at 4-50 °C

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m2 recirculation rate, 40 psi max. transmembrane pressure at 4-50 °C, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m2 recirculation rate, 40 psi max. transmembrane pressure at 4-50 °C, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m2 recirculation rate, 40 psi max. transmembrane pressure at 4-50 °C, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C

General description

Pellicon® 3 cassettes with Biomax membrane are the optimum tangential flow filtration (TFF) devices for the filtration of solutions containing therapeutical proteins, albumin, hormones, vaccines and growth factors. These advanced, high-performance cassettes are ideal for today’s higher titer therapeutic antibodies, higher viscosity feed formulations as well as the more demanding filtration processes that require higher operating pressures, temperatures and caustic cleaning regimes.From small-scale to full-scale production, Pellicon® 3 cassettes are designed for use in research, process scale-up/scale-down, applications development and full-scale manufacturing. The Pellicon® 3 design and automated manufacturing process provides unbeatable performance consistency between cassette sizes. Pellicon® 3 devices also offer greater cassette size selection for improved scale-up and scale-down process development. The streamlined design allows operators to quickly and easily handle, install and remove Pellicon® 3 cassettes. The materials of construction are compatible with a broad range of chemical cleaning.

Application

monoclonal antibodies, recombinant and non-recombinant proteins, vaccines

Features and Benefits

  • Robust, void-free membrane provides optimum productretention and performance consistency
  • Unique feed screen design enables high mass transfer, flux for higher finalconcentration
  • Fast, reliable scale up/down from lab to production scale
  • Automated manufacturing delivers unbeatable performance consistency andreliability
  • Easy to install and clean
  • Extreme temperature and chemical compatibility

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Analysis Note

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Legal Information

BIOMAX is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

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