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Viresolve® Pro Modus 2.2

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Viresolve® Pro Magnus 2.2 Device


PVDF housing
polyethersulfone membrane
silicone gasket

Quality Level

product line





60 psig max. inlet pressure


(Large volume processing)


9.50 cm (3.74 in.)


34.29 cm (13.50 in.)


20.96 cm (8.25 in.)

device size

2.2 in.

filtration area

1.53 m2


<0.25 EU/mL USP bacterial endotoxins (LAL test, sample aqueous extraction)


1.5 in. sanitary TC inlet/outlet fitting(s) (Disposable)
3/4 in. sanitary TC vent fitting for port (disposable)

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General description

The Viresolve® Pro Solution provides a comprehensive, flexible template solution for viral clearance within mAb and recombinant protein bioproduction. This proven viral clearance solution delivers the highest levels of retention assurance and productivity across a broad range of feed stream characteristics.

Viresolve Pro Magnus Devices are typically used for filtration of mid to large scale batch volumes of proteins. The Viresolve® Pro Magnus 2.2 Device offers a filtration area of 1.53 m2 and has a primary use in large-volume processing.

Features and Benefits

  • Large scale manufacturing
  • Two different size formats
  • Integrated gaskets
  • Units are stackable in the Viresolve® Pro/Pro+ Magnus Holder (up to 7 units)
  • Alignment keys on each unit to minimize errors during installation
  • Fully disposable single-use fluid path
  • Devices 100% tested with air/water diffusion and Binary Gas Test
  • Shield / Shield H 100% aerosol tested

Other Notes

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.
Directions for Use

  • Organism Retention: Parvovirus
  • Mode of Action: Filtration (size exclusion)
  • Application: Protein purification
  • Intended Use: Viral clearance
  • Instructions for Use: Please see the user guide shipped with this product
  • Storage Statement: Store at room temperature
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.

Preparation Note

This product was manufactured with materials that meet the criteria for a "non-fiber releasing" filter as defined in 21 CFR 210.3 (b) (6).

Analysis Note

After a controlled water flush of 50 L/m², samples exhibited less than 500 ppb TOC per USP <64> and less than 1.3 µS/cm per USP <64>.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
VIRESOLVE is a registered trademark of Merck KGaA, Darmstadt, Germany


EMD Millipore Corporation certifies that this product complies with the European Pressure Equipment Directive, 97/23/EC of 29 May 1997. This product has been classified under Article 3 § 3 of the Pressure Vessel Directive. It has been designed and manufactured in accordance with sound engineering practice to ensure safe use. In compliance with Article 3 § 3 of this Pressure Vessel Directive, this product does not bear the CE mark.

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