MilliporeSigma
All Photos(1)

Documents

NADP-RO

Roche

NADP

Disodium salt

Sign Into View Organizational & Contract Pricing

Synonym(s):
β-Nicotinamide adenine dinucleotide phosphate disodium salt, β-NADH phosphate disodium salt, β-NADP-Na2, Triphosphopyridine nucleotide disodium salt
Empirical Formula (Hill Notation):
C21H26N7Na2O17P3
CAS Number:
Molecular Weight:
787.37
MDL number:
PubChem Substance ID:

Quality Level

assay

≥97%

form

powder

mol wt

Mr 743.4
Mr 787.4

packaging

pkg of 1 g (10128058001)
pkg of 100 mg (10128031001)
pkg of 5 g (10240354001)
pkg of 500 mg (10128040001)

manufacturer/tradename

Roche

pH

4.0 ± 1.0(10mg/mL)

λmax

260 nm

shipped in

wet ice

storage temp.

2-8°C

SMILES string

[Na+].[Na+].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP(O)([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H28N7O17P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;/q;2*+1/p-2/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1

InChI key

WSDDJLMGYRLUKR-FHQWUTKFSA-L

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1.24541481972481971-M
vibrant-m

NADP-RO

NADP

vibrant-m

481972

NADP, Disodium Salt

vibrant-m

481971-M

NADP, Monosodium Salt

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mol wt

Mr 743.4, Mr 787.4

mol wt

-

mol wt

-

mol wt

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

shipped in

wet ice

shipped in

-

shipped in

ambient

shipped in

-

assay

≥97%

assay

≥95.0% dry basis (enzymatic)

assay

≥95% (enzymatic)

assay

≥92% (enzymatic), ≥95% (UV)

General description

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.

Application

The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.

Preparation Note

Storage conditions (working solution): 2 to 8 °C
10 mg/ml in aqueous solution, contains at least 99% NADP after 4 weeks at 2 to 8 °C

Analysis Note

Absorbance coefficients: 18.0 x 103 [l x mol-1 x cm-1] at 260 nm, 5.9 x 103 [l x mol-1 x cm-1] at 333 nm (CN complex)

Absorbance at 340 nm: Imidazol buffer, 100 mM pH 6.7, NADP 2 mM (= 14.87 mg/10 ml) : A340 approximately 0.100.

Absorbance at 360 nm: Aqueous solution of NADP, 10 mg/ml: A360 approximately 0.200-0.250.

Other Notes

For life science research only. Not for use in diagnostic procedures.

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Redox modulation of glucose-6-P dehydrogenase in Anacystis nidulans and its 'uncoupling' by phage infection.
C Cséke et al.
FEBS letters, 126(1), 85-88 (1981-04-06)
Malgorzata Adamczyk et al.
Methods in enzymology, 500, 233-257 (2011-09-29)
In vitro enzymatic assays of cell-free extracts offer an opportunity to assess in vivo enzyme concentrations. If performed under conditions that resemble the conditions in vivo, they may also reveal some of the capacities and properties of the same enzymes
Jinrui Zhang et al.
Scientific reports, 5, 12846-12846 (2015-08-06)
Eukaryotic metabolism is organised in complex networks of enzyme catalysed reactions which are distributed over different organelles. To quantify the compartmentalised reactions, quantitative measurements of relevant physiological variables in different compartments are needed, especially of cofactors. NADP(H) are critical components
Lin Zhu et al.
American journal of physiology. Endocrinology and metabolism, 306(10), E1188-E1197 (2014-04-03)
The development of insulin resistance in the liver is a key event that drives dyslipidemia and predicts diabetes and cardiovascular risk with obesity. Clinical data show that estrogen signaling in males helps prevent adiposity and insulin resistance, which may be

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service