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00190585

Hypericin

primary reference standard

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Synonym(s):
4,5,7,4′,5′,7′-Hexahydroxy-2,2′-dimethylnaphthodianthrone
Empirical Formula (Hill Notation):
C30H16O8
CAS Number:
Molecular Weight:
504.44
Beilstein/REAXYS Number:
1917913
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

storage temp.

−20°C

SMILES string

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

InChI

1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

InChI key

BTXNYTINYBABQR-UHFFFAOYSA-N

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Hypericin primary reference standard

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Hypericin phyproof® Reference Substance

PHL89226

Hypericin

Hypericin from Hypericum perforatum ~95% (HPLC)

56690

Hypericin from Hypericum perforatum

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

manufacturer/tradename

HWI

manufacturer/tradename

Calbiochem®

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

General description

Produced by HWI Analytik
Exact content can be found on the certificate

Application

It was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.
Reference standard in the analysis of herbal medicinal products.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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J B Hudson et al.
Antiviral research, 15(2), 101-112 (1991-02-01)
Hypericin, a photodynamic plant quinone, readily inactivated murine cytomegalovirus (MCMV), Sindbis virus, and human immunodeficiency virus type 1 (HIV-1), especially on exposure to fluorescent light. Sindbis virus was significantly more sensitive than MCMV. The inactivated MCMV, when used to infect
D E Gray et al.
Journal of AOAC International, 83(4), 944-949 (2000-09-20)
Hypericin and hyperforin are believed to be among the active constituents in common St. John's wort (Hypericum perforatum L.). Presently, dietary supplements are generally standardized to contain specified levels of hypericin and hyperforin, and the related compounds, pseudohypericin and adhyperforin.
Pavol Miskovsky
Current drug targets, 3(1), 55-84 (2002-03-20)
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent interest in hypericin is provoked by the discovery that it possesses extremely
Theodossis A Theodossiou et al.
Molecular pharmaceutics, 6(6), 1775-1789 (2009-09-11)
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin (photosensitizer), visible light and oxygen. The latter is photochemically converted into reactive oxygen species, which are highly toxic to the cells. Hypericin, a natural pigment of hypericum plants, is
Binghu Jiang et al.
Theranostics, 3(9), 667-676 (2013-09-21)
Hypericin has been widely studied as a potent photosensitizer for photodynamic therapy in both preclinical and clinical settings. Recently, hypericin has also been discovered to have a specific avidity for necrotic tissue. This affinity is also observed in a series

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