Skip to Content
MilliporeSigma
All Photos(1)

Documents

03685

Sigma-Aldrich

Ethylenediaminetetraacetic acid disodium salt dihydrate

≥97.0% (KT)

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2
Empirical Formula (Hill Notation):
C10H14N2Na2O8 · 2H2O
CAS Number:
6381-92-6
Molecular Weight:
372.24
Beilstein/REAXYS Number:
3900609
EC Number:
205-358-3
UNSPSC Code:
12352100
PubChem Substance ID:
24845550
NACRES:
NA.21

Quality Level

300

assay

≥97.0% (KT)

mp

248 °C (dec.) (lit.)

solubility

H2O: 100 g/L at 20 °C

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Ethylenediaminetetraacetic acid disodium salt dihydrate (EDTA-Na2), is a well known complexation agent with various uses in chemical synthesis, analytical chemistry, and biochemistry. In chemical synthesis, EDTA-Na2 combines with polyvalent cations to form a soluble non-ionic complex that can be removed from solution, which helps prevent undesired side reactions.

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H332,H373

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

target_organs

Respiratory Tract

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Suli Huang et al.
PloS one, 10(2), e0117007-e0117007 (2015-02-07)
microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported.
G Lima-Oliveira et al.
British journal of biomedical science, 70(1), 6-9 (2013-04-27)
This study assesses the use of different dry K2 (dipotassium) EDTA vacuum tubes and whether or not they might represent a bias in haematological testing. Blood was collected in three dipotassium EDTA vacuum tubes from different manufacturers: Venosafe, Vacuette and
Lisa M Ryno et al.
Biomacromolecules, 15(8), 2944-2951 (2014-07-18)
End-functionalized macromolecular starch reagents, prepared by reductive amination, were grafted onto a urethane-linked polyester-based backbone using copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry to produce novel amphiphilic hybrid graft copolymers. These copolymers represent the first examples of materials where the pendant chains
Haiyan Zhang et al.
Analytica chimica acta, 770, 140-146 (2013-03-19)
A novel method for selective determination of Cr(III) and Cr(VI) in environmental water samples was developed based on target-induced fluorescence quenching of glutathione-stabilized gold nanoclusters (GSH-Au NCs). Fluorescent GSH-Au NCs were synthesized by a one-step approach employing GSH as reducing/protecting
Gervasio A Lamas et al.
JAMA, 309(12), 1241-1250 (2013-03-28)
Chelation therapy with disodium EDTA has been used for more than 50 years to treat atherosclerosis without proof of efficacy. To determine if an EDTA-based chelation regimen reduces cardiovascular events. Double-blind, placebo-controlled, 2 × 2 factorial randomized trial enrolling 1708
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service