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03971

Sigma-Aldrich

Hematoxylin solution according to Delafield

for microscopy

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Synonym(s):
Delafield’s hematoxylin
Beilstein/REAXYS Number:
91401
MDL number:
PubChem Substance ID:
NACRES:
MA.02

grade

for microscopy

Quality Level

product line

BioChemika

form

liquid

technique(s)

microbe id | staining: suitable

impurities

ammonium alum
methanol

density

0.950-1.044 g/mL at 20 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

suitability

Chlamydia spp.
Histoplasma spp.
Plasmodium spp.
Trichomonas spp.
bacteria
protozoa
spirochetes

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

General description

Hematoxylin solution according to Delafield is a naturally ripened alum hematoxylin with potassium alum or ammonium alum as the mordant. It is used when the counterstain doesn′t possess any acid content in it. It is suitable to be used as a nuclear stain with eosin.

Application

Hematoxylin solution according to Delafield has been used to stain the nuclei of different sections of adipose tissue for its histochemical analysis. It is suitable for staining thick or thin blood films. It is also frequently used to stain and study the visibility of microfilariae.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

107.6 °F - closed cup

flash_point_c

42 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Lijun Dong et al.
Inflammation, 40(6), 1944-1958 (2017-09-04)
T cells are involved in chronic inflammation of adipose tissue in obese conditions. However, the impact of age on the adipose T cells remains unknown. In this study, we investigated T cells in the white adipose tissue of young and
Hongling Zhu et al.
Experimental and therapeutic medicine, 14(4), 3609-3615 (2017-10-19)
Basic fibroblast growth factor (bFGF), a known angiogenic factor, may provide a potential strategy for the treatment of myocardial infarction (MI), but it is limited by a relatively short half-life. Dex-PCL-HEMA/PNIPAAm hydrogel provides a reservoir for the controlled release of
Niina Vuokila et al.
Cellular and molecular life sciences : CMLS, 75(24), 4557-4581 (2018-08-30)
Traumatic brain injury (TBI) initiates molecular and cellular pathologies that underlie post-injury morbidities, including hippocampus-related memory decline and epileptogenesis. Non-coding small RNAs are master regulators of gene expression with the potential to affect multiple molecular pathways. To evaluate whether hippocampal
Li-Gen Lin et al.
Journal of medicinal chemistry, 51(15), 4419-4429 (2008-07-10)
Protein tyrosine kinase (PTK) inhibitors represent emerging therapeutics for cancer chemoprevention. In our study, hematoxylin (26) was identified as one of the most remarkable c-Src inhibitors in an orthogonal compound-mixing library (32200 compounds) by using an ELISA-based automated high-throughput screening
Hideki Ishii et al.
Bioorganic & medicinal chemistry letters, 22(3), 1469-1474 (2012-01-17)
SAR studies for the exploration a novel class of anti-human immunodeficiency virus type 1 (HIV-1) agents based on the hematoxylin structure (1) are described. The systematic deoxygenations of 1 including asymmetric synthesis were conducted to obtain a compound showing high

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