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Supelco

4-Aminoantipyrine

for spectrophotometric det. of H2O2 and phenols, ≥98.0%

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Synonym(s):
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
Molecular Weight:
203.24
Beilstein/REAXYS Number:
181635
EC Number:
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.21

Quality Level

assay

≥98.0% (NT)
≥98.0%

quality

for spectrophotometric det. of H2O2 and phenols

technique(s)

UV/Vis spectroscopy: suitable
photometry: suitable

mp

105-110 °C (lit.)
108-110 °C

solubility

H2O: 0.1 g/mL, clear to slightly hazy

SMILES string

CN1N(c2ccccc2)C(=O)C(N)=C1C

InChI

1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3

InChI key

RLFWWDJHLFCNIJ-UHFFFAOYSA-N

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Application


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  • Tramadol and M1 Bioavailability Induced by Metamizole Co-Administration in Donkeys (Equus asinus).: This study explores the pharmacokinetic interactions between tramadol and metamizole in donkeys, offering insights into veterinary medicine and drug administration practices (Araújo-Silva et al., 2024).

  • Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva - A Case Study.: This paper presents a methodological innovation using saliva samples to optimize pediatric dosing of medications, which could revolutionize therapeutic drug monitoring in children (Anliker-Ort et al., 2024).

  • Spectrophotometric determination of phenol impurity in phenoxyethanol and phenol index of drinking water and municipal wastewater effluent after salting-out assisted liquid phase microextraction (SA-LPME).: This study offers a spectrophotometric method for detecting phenol impurities, enhancing water quality monitoring techniques (Roustaei et al., 2024).

  • A novel hybrid sensor array based on the polyphenol oxidase and its nanozymes combined with the machine learning based dual output model to identify tea polyphenols and Chinese teas.: This research introduces a hybrid sensor array employing polyphenol oxidase and its nanozymes for detecting tea polyphenols, showcasing the integration of enzymatic methods with machine learning for enhanced specificity and sensitivity in food analysis (Yang et al., 2024).

Other Notes

4-Aminoantipyrine has been used as a corrosion inhibitor of mild steel in 2 M HCl solution using different techniques: electrochemical impedance spectroscopy (EIS), potentiodynamic polarization and weight loss.
Reagent for the determination of H2O2

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Amberlite IRA 900 anion-exchange resin modified with manganese-tetrakis(sulphophenyl)-porphine has been used as a catalyst instead of peroxidase for the determination of hydrogen peroxide by the reaction 2H(2)O(2) + N,N-diethylaniline + 4-aminoantipyrine (catalyst)--> quinonoid dye (lambda(max) 550 nm) + 4H(2)O. The
Stephanie Hackett et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73(7), e2217-e2225 (2020-08-01)
Children living with human immunodeficiency virus (HIV) (CLHIV) receiving antiretroviral therapy (ART) in resource-limited settings are susceptible to high rates of acquired HIV drug resistance (HIVDR), but few studies include children initiating age-appropriate World Health Organization (WHO)-recommended first-line regimens. We

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