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08062

Sigma-Aldrich

Protein G′ from Streptococcus sp.

recombinant, expressed in E. coli

Synonym(s):

IgG F(c)-Receptor

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About This Item

MDL number:
MFCD00132110
UNSPSC Code:
12352202
NACRES:
NA.26
Pricing and availability is not currently available.

biological source

bacterial (Streptococcus sp.)

Quality Level

100

recombinant

expressed in E. coli

form

lyophilized solid

mol wt

~30 kDa

capacity

~5 mg/mg, solid binding capacity (IgG)

storage temp.

−20°C

General description

Genetically engineered truncated protein G; retains affinity for IgG, but lacks albumin and Fab binding sites and membrane-binding regions.
Protein G, a cell wall protein,[1] is obtained from group G streptococci.[2] The extracellular part of this protein is made of two/three small domains or serum albumin binding (GA domains) and two/three immunoglobulin (IgG) binding domains (B domains).[1]

Application

Protein G′ from Streptococcus sp. has been used in in vitro actin labeling assay.[3]

Biochem/physiol Actions

Protein G can bind all the human and mouse IgG subclasses.[2] It can bind to both the fragment crystallizable (Fc) and antigen-binding fragment (Fab) components of the antibody.[1]

Physical form

lyophilized powder in a Tris-HCl buffer, pH 7.5

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6248
BCCM6247
BCCL3355
BCCL0177
BCCG8269

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