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15222

Supelco

N,O-Bis(trimethylsilyl)trifluoroacetamide

for GC derivatization, LiChropur, ≥99.0%

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Synonym(s):
BSTFA
Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
Molecular Weight:
257.40
Beilstein:
2050024
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

grade

for GC derivatization

Quality Level

Assay

≥99.0% (GC)
≥99.0%

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.384 (lit.)
n20/D 1.384

bp

45-50 °C/14 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

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This Item
155195B-02315209
BSTFA (with 1% TMCS) kit of 10 × 1 mL, analytical standard, Cerilliant®

Supelco

B-023

BSTFA (with 1% TMCS)

form

liquid

form

liquid

form

-

form

liquid

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

-

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

density

0.969 g/mL at 25 °C (lit.)

density

0.969 g/mL at 25 °C (lit.)

density

0.97 g/mL (lit.)

General description

N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is an excellent silylation reagent. For some sterically hindered primary or secondary nitro compounds, N,O-bis(trimethylsilyl)acetamide and BSTFA achieve better results than normal silylation conditions. BSTFA finds application in derivatizing amines. It is suitable for silyaltion of carboxylic acids, phenols, ureas, amides and alcohols.

Application

Learn more in the Product Information
BSTFA + 1% TMCS (trimethylsilyl) in ethyl acetate, acetonitrile and dichloromethane solvents may be used for silylation of steroid hormone 17a-ethinylestradiol (EE2) using gas chromatography-mass spectrometry (GC-MS). It may also be used for silylation of endogenous 2-monoglyceride, present in canine gut that binds to cannabinoid receptors.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

accessory

Product No.
Description
Pricing

related product

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

93.2 °F

Flash Point(C)

34 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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