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D-(+)-Cellobiose

≥99.0%, suitable for microbiology, Reducing sugar disaccharide

Synonym(s):

Cellobiose, Cellose, Beta-Cellobiose, D-Cellobiose, β-D-Glc-(1→4)-D-Glc, 4-O-β-D-Glucopyranosyl-D-glucose

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein/REAXYS Number:
93795
EC Number:
MDL number:
UNSPSC Code:
41106212
PubChem Substance ID:
NACRES:
NA.85

Quality Level

assay

≥99.0% (HPLC)
≥99.0%

form

powder

optical activity

[α]20/D +34±1°, 15 hr, c = 10% in H2O

mol wt

342.30 g/mol

ign. residue

≤0.1% (as SO4)

loss

≤1% loss on drying, 110 °C

mp

~235 °C (dec.)
239 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤150 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

microbiology

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12-/m0/s1

InChI key

DKXNBNKWCZZMJT-WELRSGGNSA-N

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General description

Cellobiose is a disaccharide that is a reducing sugar. It is added to culture media as a nutrient supplement, specifically as a carbohydrate source, and can be used to differentiate bacteria based on their ability to ferment cellobiose. For example, Vibrio spp. can ferment cellobiose which results in acid production and can be indicated by the pH indicator bromothymol blue, which turns yellow at acidic pH. The addition of cellobiose in the media also stimulates the initial growth of Salmonella.

Application

Cellobiose has applications as a carbohydrate source in culture media and biochemical characterization of microorganisms, based on their carbohydrate fermentation abilities

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Corinna Schiano-di-Cola et al.
The FEBS journal, 287(12), 2577-2596 (2019-11-23)
Thermostable cellulases from glycoside hydrolase family 7 (GH7) are the main components of enzymatic mixtures for industrial saccharification of lignocellulose. Activity improvement of these enzymes via rational design is a promising strategy to alleviate the industrial costs, but it requires
Sylvie Estrela et al.
eLife, 10 (2021-04-21)
A major open question in microbial community ecology is whether we can predict how the components of a diet collectively determine the taxonomic composition of microbial communities. Motivated by this challenge, we investigate whether communities assembled in pairs of nutrients
Benjamin J Matthews et al.
eLife, 8 (2019-05-22)
Female Aedes aegypti mosquitoes are deadly vectors of arboviral pathogens and breed in containers of freshwater associated with human habitation. Because high salinity is lethal to offspring, correctly evaluating water purity is a crucial parenting decision. We found that the
Amika Sood et al.
Journal of chemical information and modeling, 58(9), 1889-1901 (2018-08-08)
Protein-carbohydrate interactions are significant in a wide range of biological processes, disruption of which has been implicated in many different diseases. The capability of glycan-binding proteins (GBPs) to specifically bind to the corresponding glycans allows GBPs to be utilized in
Lara Hassan et al.
mBio, 10(4) (2019-07-04)
It is essential for microbes to acquire information about their environment. Fungi use soluble degradation products of plant cell wall components to understand the substrate composition they grow on. Individual perception pathways have been well described. However, the interconnections between

Articles

Culture media provides a habitat with suitable nutrients, energy sources, and certain environmental conditions for the growth of microorganisms. The components of the culture media range from simple sugars to peptones, salts, antibiotics, and complex indicators.

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