25107

Potassium citrate tribasic monohydrate

meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)

• Synonym(s): Citric acid tripotassium salt, Tripotassium citrate
• Linear Formula: HOC(COOK)(CH₂COOK)₂ · H₂O
• CAS Number: 6100-05-6
• Molecular Weight: 324.41
• Beilstein/REAXYS Number: 3924344
• EC Number: 231-905-0
• MDL number: MFCD00150442
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648111
• NACRES: NA.21

Properties

• Quality Level: 200
• assay: 99-100.5% (calc with ref. to anhyd. subst.)
• form: powder or crystals
• quality: meets analytical specification of Ph. Eur., BP, FCC, E332
• impurities: ≤0.0005% heavy metals (as Pb); 4-6% water (Karl Fischer)
• loss: 3-6 loss on drying, 180°C
• pH: 7-9 (20 °C, 5%)
• mp: 275 °C (dec.) (lit.)
• solubility: glycerol: soluble 1 gm in 2.5 ml; water: soluble 1 gm in 0.65 ml; alcohol: insoluble
• anion traces: chloride (Cl^-): ≤30 mg/kg; oxalate (as oxalic acid): ≤100 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg

Description

Application

Potassium citrate tribasic monohydrate has been used for preparing citrate-supplemented water for feeding the Car5A, Car5B, and DKO breeding pairs of mice. Citrate supplementation enhances the perinatal death in mice.[1] It is a citrate-based salt used as a phase constituent for characterizing ionic-liquid-based aqueous biphasic systems (ABS)[2] and as a buffering agent.[3]

Biochem/physiol Actions

Potassium citrate tribasic monohydrate is the potassium salt of citric acid. It enhances the bone density hence used in the treatment of osteoporosis.[4] Additionally, it neutralizes the protein-induced metabolic acidosis.[5]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)