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31592

Supelco

Amprolium hydrochloride

VETRANAL®, analytical standard

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Synonym(s):
1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride
Linear Formula:
C14H19N4Cl · HCl
CAS Number:
Molecular Weight:
315.24
Beilstein/REAXYS Number:
4118699
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

description

cationic

product line

VETRANAL®

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

mol wt

315.24 g/mol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thiamine (vitamin B1) deficiency (TD) causes region selective neuronal loss in the brain; it has been used to model neurodegeneration that accompanies mild impairment of oxidative metabolism. The mechanisms for TD-induced neurodegeneration remain incompletely elucidated. Inhibition of protein glycosylation, perturbation
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Veterinary parasitology, 178(3-4), 346-349 (2011-02-22)
This study evaluated the efficacy of two different doses of amprolium in goats heavily infected with pathogenic Eimeria species. Forty Boer goat kids ranging from 3 to 5 months of age with naturally occurring coccidiosis were randomly divided into 2
D Bizon-Zygmańska et al.
Neurochemistry international, 59(2), 208-216 (2011-06-16)
Inhibition of pyruvate (PDHC) and ketoglutarate (KDHC) dehydrogenase complexes induced by thiamine pyrophosphate deficits is known cause of disturbances of cholinergic transmission in the brain, yielding clinical symptoms of cognitive, vegetative and motor deficits. However, particular alterations in distribution of
N E Nweze et al.
Journal of ethnopharmacology, 122(1), 6-9 (2008-12-17)
Ageratum conyzoides (Asteraceae) is folklorically used to treat diseases associated with bleeding. A study was conducted to determine the efficacy of Ageratum conyzoides in treating caecal coccidiosis of broilers. Acute toxicity test was done using thirty 28 days old broiler
Clara Lemos et al.
European journal of pharmacology, 682(1-3), 37-42 (2012-03-06)
The aim of this study was to characterize the intestinal absorption of thiamine, by investigating the hypothesis of an involvement of Organic Cation Transporter (OCT) family members in this process. [(3)H]-T(+) uptake was found to be: 1) time-dependent, 2) Na(+)-

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