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31626

Supelco

Bacitracin A

VETRANAL®, analytical standard, main stereoisomer ~50 %

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About This Item

Empirical Formula (Hill Notation):
C66H103N17O16S
Molecular Weight:
1422.69
EC Number:
245-115-9
UNSPSC Code:
41116107
PubChem Substance ID:
24869751
E Number:
E700
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

composition

main stereoisomer, ~50%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

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General description

Bacitracin is a polypeptide antibiotic produced by strains of Bacillus subtilis and Bacillus licheniformis. Bacitracin A is a commercially produced, major microbiologically active component of bacitracin.

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ5801
BCCH4525
BCBZ5316
BCBZ6516

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Walter Mancino et al.
Microorganisms, 7(12) (2019-12-08)
Specific members of the genus Bifidobacterium are among the first colonizers of the human/animal gut, where they act as important intestinal commensals associated with host health. As part of the gut microbiota, bifidobacteria may be exposed to antibiotics, used in
Mukundan Ragavan et al.
Analytical chemistry, 83(15), 6054-6059 (2011-06-10)
Hyperpolarization of nuclear spins through techniques such as dynamic nuclear polarization (DNP) can greatly increase the signal-to-noise ratio in NMR measurements, thus eliminating the need for signal averaging. This enables the study of many dynamic processes which would otherwise not
A M Neumüller et al.
European journal of biochemistry, 268(11), 3180-3189 (2001-06-08)
Bacitracin is a peptide antibiotic produced by several Bacillus licheniformis strains that is most active against other Gram-positive microorganisms, but not against the producer strain itself. Recently, heterologous expression of the bacitracin resistance mediating BcrABC transporter in Bacillus subtilis and
Cindy Govaerts et al.
Rapid communications in mass spectrometry : RCM, 17(12), 1366-1379 (2003-06-18)
A selective reversed-phase liquid chromatography/mass spectrometry (LC/MS(n)) method is described for the characterization of related compounds in commercial bacitracin samples. Mass spectral data for these polypeptide antibiotics were acquired on a LCQ ion trap mass spectrometer equipped with an electrospray
Massimo Castagnola et al.
Electrophoresis, 25(6), 846-852 (2004-03-09)
Thermodynamics of the binding of Ni(2+), Cu(2+) and Zn(2+) to bacitracin A(1) was studied by capillary electrophoresis measuring the peptide effective mobility at different pH in the presence of increasing concentration of the three ligands. The affinity follows the order
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