32201-M

Acetone

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

• Linear Formula: CH₃COCH₃
• CAS Number: 67-64-1
• Molecular Weight: 58.08
• Beilstein/REAXYS Number: 635680
• EC Number: 200-662-2
• MDL number: MFCD00008765
• UNSPSC Code: 12352115
• eCl@ss: 39021201
• PubChem Substance ID: 329754097
• NACRES: NA.02
• assay: ≥99.5% (GC)
• technique(s): UV/Vis spectroscopy: suitable
• bp: 56 °C/760 mmHg (lit.)
• vapor pressure: 184 mmHg ( 20 °C)

Properties

• grade: ACS reagent; puriss. p.a.
• agency: USP/NF; reag. ISO; reag. Ph. Eur.
• vapor density: 2 (vs air)
• vapor pressure: 184 mmHg ( 20 °C)
• assay: ≥99.5% (GC)
• form: liquid
• expl. lim.: 13.2 %
• technique(s): UV/Vis spectroscopy: suitable
• impurities: ≤0.0002% KMnO₄ red. matter (as O); ≤0.0002% benzene; ≤0.0008% free alkali (as NH₃); ≤0.001% aldehydes (as HCHO); ≤0.001% non-volatile matter; ≤0.0015% free acid (as CH₃COOH); ≤0.01% ethanol (GC); ≤0.05% 2-propanol; ≤0.05% methanol; ≤0.2% water (Karl Fischer)
• refractive index: n20/D 1.3580-1.3600; n20/D 1.359 (lit.)

Description

General description

Mixtures of TiO₂ (P25) with rare earth oxides (La₂O₃ or Y₂O₃) calcined at 700°C or 650°C have been reported to efficiently photocatalyze oxidation of acetone.[1] Its aldol condensation in vapor-phase has been investigated over MgO promoted with alkali (Li, Na, K and Cs) or alkaline earth (Ca, Sr and Ba) metal ions.[2] It undergoes Aldol condensation in the presence of Mg-Al layered double hydroxides (LDH) as catalysts and Cl^- and/or CO₃^2- as compensating anions to afford diacetone alcohol and mesityl oxide.[3] Enantioselective Aldol condensation of acetone with various isatins in the presence of dipeptides (catalyst) has been described.[4]

Application

Acetone was used in the synthesis of Ga (Gallium)-DOTATATE (where DOTA=1,4,7,10-tetraazacyclo- dodecane -1,4,7,10-tetraacetic acid) chemicals.[5] It may be used in an assay for determination of ester groups in lipids by spectrophotometric methods.[6]

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319,H336
• pcodes: P210 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17.00 °C - closed cup